Abstract
IT is commonly stated that calves are born without γ-globulin and that the bovine fœtus is unable to produce antibodies. The first part of the statement is invalidated by the detection of measurable amounts of γ-globulin in pre-colostral serum of new-born calves1–3. The question whether this globulin has been developed by the calf or passively acquired in utero was left open by Pierce3. Little and Orcutt4 found Brucella agglutinins in pre-colostral serum of a premature Brucella-infected calf and in serum of aborted fœtuses from Brucella-infected cattle, but expressed no opinion about the origin of these antibodies.
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References
San Clemente, C. L., and Huddleson, I. F., Michigan Agric. Exp. Sta. Tech. Bull. 182, 3 (1943).
Hansen, R. G., and Phillips, P. H., J. Biol. Chem., 171, 223 (1947).
Pierce, A. E., J. Hyg., 53, 247 (1955).
Little, R. B., and Orcutt, M. L., J. Exp. Med., 35, 161 (1922).
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FENNESTAD, K., BORG-PETERSEN, C. Leptospira Antibody Production by Bovine Fœtuses. Nature 180, 1210–1211 (1957). https://doi.org/10.1038/1801210a0
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DOI: https://doi.org/10.1038/1801210a0
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