Abstract
THE presence of a hyperglycæmic substance in the blood of the pancreaticoduodenal and portal veins of animals treated with growth hormone has been reported by Bornstein, Reid and Young1 and by Foa, Magid, Glassman and Weinstein2. These authors have been commendably cautious in the interpretation of their findings; but the inference that this hyperglycæmic substance is glucagon has been made by many who have discussed these papers.
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Bornstein, J., Reid, E., and Young, F. G., Nature, 168, 903 (1951).
Foa, P. P., Magid, E. B., Glassman, M. D., and Weinstein, H. R., Proc. Soc. Exp. Biol. and Med., 83, 758 (1953).
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Sirek, O. V., Sirek, A., and Best, C. H., Amer. J. Physiol. (in the press).
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Weitzel, G., Roester, U., Buddecke, E., and Strecker, F. J., Hoppe-Seylers Z. physiol. Chem., 303, 161 (1956).
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SIREK, A. Nature and Site of Origin of the Hyperglycæmic Substance released following an Injection of Growth Hormone. Nature 179, 376 (1957). https://doi.org/10.1038/179376a0
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DOI: https://doi.org/10.1038/179376a0
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