Abstract
THE ideal substance for evaluation of haemagglutination by means of a density column must not enhance rouleaux formation or produce haemolysis (osmotic fragility ; mechanical fragility). Such a substance should not increase the sedimentation of single cells, but only of aggregates. Previous work1 has shown that fibrinogen, certain gums, gelatin, glycogen, pectin, agar-agar, hyaluronic acid, polyacrylic acid and deoxyribonucleic acid are unsuitable. My own experience has shown that saccharose, dextrin, poly-vinylpyrolidone (Antara Chemicals, Boston, U.S.A.), plasdone C (Antara Chemicals, Boston, U.S.A.), dextran (Grade i.v. clinical) (R. K. Laros Co., Bethlehem, U.S.A.), methylcellulose SL 25 (Kalle and Co., Wiesbaden-Biebrich, Germany) and cellulose-glycolate KN 25 (Kalle and Co., Wiesbaden-Biebrich, Germany) are also unsuitable.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Jandl, J. H., and Castle, W. B., J. Lab. Clin. Med., 47, 669 (1956). Hale, H. T., Weisman, R., and Hinz, C. F., Arch. Int. Med., 96, 574 (1956).
Böhringer, H. R., Steiger, R., and Wunderly, Ch., Arch. f. Ophthalmol., 157, 543 (1956).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
WUNDERLY, C. Quantitative Evaluation of Hæmagglutination by means of a Density Column. Nature 179, 1132–1133 (1957). https://doi.org/10.1038/1791132a0
Issue Date:
DOI: https://doi.org/10.1038/1791132a0
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
