Abstract
THE human antiglobulin reagent described by Coombs, Mourant and Race1 was prepared in rabbits. Later, Eyquem (personal communication), Hill and Haberman2 and Dunsford (personal communication) produced reagents in goats, and Eyquem (personal communication) in donkeys. I have tried to produce a reagent in a variety of animals, including rabbits, hens, sheep and the horse. Rabbits, of course, have been used in many laboratories; but it seemed it would be an advantage if an animal could be used from which more serum was available when immunization was satisfactorily completed. Sheep were found to be satisfactory animals.
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Coombs, R. R. A., Mourant, A. E., and Race, R. R., Lancet, ii, 15 (1945).
Hill, S., and Haberman, J. M., Amer. J. Clin. Path., 24, 305 (1954).
Crawford, H., Cutbush, M., and Mollison, P. L., Brit. J. Hæm., 1, 410 (1955).
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STRATTON, F. Production of Human Antiglobulin Reagent in Sheep. Nature 178, 214 (1956). https://doi.org/10.1038/178214a0
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DOI: https://doi.org/10.1038/178214a0
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