Abstract
THE pathogenesis of most scaling skin conditions is obscure. Although it has been often assumed that abnormal processes of keratinization play a major part, recent work has emphasized the importance of the water-soluble components of the horny layer. These components contribute to the water-binding ability and pliability of the normal skin surface1; their amounts are reduced in psoriatic scales2 and skin3.
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References
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FLESCH, P., JACKSON ESODA, E. Deficient Water-binding in Pathological Horny Layers. Nature 178, 211–212 (1956). https://doi.org/10.1038/178211b0
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DOI: https://doi.org/10.1038/178211b0
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