Abstract
RECENT work of Ada and Perry1 on the nucleic acid composition of influenza virus has shown that the infectious particles lack deoxyribonucleic acid, and that they contain about 0.8 per cent of ribonucleic acid. The degree of infectiveness is, in fact, a function of the ribonucleic acid content; the ‘incomplete’ form of the virus is characterized by a low infectivity/hæmagglutination ratio, and its ribonucleic acid content is lower than that of the standard form2.
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References
Ada, G. L., and Perry, B. T., Aust. J. Exp. Biol., 32, 453 (1954).
Ada, G. L., and Perry, B. T., Nature, 175, 209 (1955).
Tamm, I., and Fluke, D. J., J. Bact., 59, 449 (1950).
Casterman, C., and Jeener, R., Biochim. Biophys. Acta, 16, 433 (1955).
Tamm, I., Folkers, K., and Horsfall, F. L., J. Exp. Med., 98, 229 (1953).
Reed, L. J., and Muench, H., Amer. J. Hyg., 27, 493 (1938).
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LE CLERC, J. Action of Ribonuclease on the Multiplication of the Influenza Virus. Nature 177, 578–579 (1956). https://doi.org/10.1038/177578b0
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DOI: https://doi.org/10.1038/177578b0
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