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5-Hydroxytryptamine: its Occurrence in Cowhage

Nature volume 174, pages 925–926 (1954)Cite this article

Abstract

THE trichomes from the pods of Mucuna pruriens DC, which constitute cowhage, have long been known to cause intense itching, and some pain, when applied to the human skin. Broadbent1 concluded, from pharmacological and histological studies, that the itching was not a mechanical effect of the trichomes but was due to the presence of a histamine-liberating substance.

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Authors and Affiliations

  1. Department of Organic Chemistry,

    K. BOWDEN

  2. Department of Pharmacology, University of Leeds,

    BARBARA G. BROWN & JEAN E. BATTY

Authors
  1. K. BOWDEN
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  2. BARBARA G. BROWN
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  3. JEAN E. BATTY
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BOWDEN, K., BROWN, B. & BATTY, J. 5-Hydroxytryptamine: its Occurrence in Cowhage. Nature 174, 925–926 (1954). https://doi.org/10.1038/174925a0

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