Abstract
PUBLISHED information on the results of investigation of the toxic and narcotic activity of fluorocarbons is very scanty, and such as is available is probably invalidated because of the lack of purity of the samples used in the tests. Struck and Plattner1, who examined C4F10, C5F10 and C6F12, concluded that the materials were toxic, whereas Spiegl2 used concentrations of C7F16 and C8F16 which were too low to acquit them of toxic properties. He fotind C7F14, of unspecified purity, to be toxic.
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References
Struck, H. C., and Plattner, E. B., J. Pharmacol. and Exp. Therap., 68, 217 (1940).
Spiegl, C. J., “National Nuclear Energy Series VI–I”, edit. Voegtlein and Hodge, Chapter 28, p. 2291 (McGraw-Hill, 1953).
Sarsfield, N. F., assignor to I.C.I., Ltd., Brit. Pat. 621, 555.
Bradbury, F. R., and Armstrong, G., Ann. App. Biol., 41 (1), 65 (1954).
Mullins, L. H., Chem. Rev., 54, 289 (1954).
Grafstein, G., Anal. Chem., 26, 523 (1954).
Symposium “Mécanisme de la narcose”, Paris, April 19–26, 1950, p. 25.
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BANKS, A., CAMPBELL, A. & RUDGE, A. Toxicity and Narcotic Activity of Fluorocarbons. Nature 174, 885 (1954). https://doi.org/10.1038/174885a0
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DOI: https://doi.org/10.1038/174885a0
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