Abstract
It has been known for some time that histologically demonstrable activation of the thyroid may be produced in rats1, guinea pigs and other mammals2 upon their being subjected to cold for a period of various days. It is also known that this activation takes place by the mediation of the hypophysis3. Recent investigations, in which quantitative methods were employed (measures of the average height of the epithelium), led to the conclusion that in order to bring about significant changes the cold should be applied for at least three days4.
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CONTE, E., STUX, M. Rapidity of Thyroid Reaction to Cold. Nature 173, 83 (1954). https://doi.org/10.1038/173083a0
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DOI: https://doi.org/10.1038/173083a0
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