Abstract
IN a previous communication, Parmentier and Dustin1 reported a mitotic anomaly in the mouse intestine produced by hydroquinone. The characteristic feature of this was the so-called ‘three-group metaphase’, comprising a normal metaphase plate with additional chromosome particles or groups at each pole of the spindle. One of the authors afterwards described the same phenomenon in the intestine and bone marrow of the golden hamster2. According to the latter, characteristic ‘three-group metaphases’ may also be produced in the rat, whereas “the guinea pig, the chick and chick fibroblast cultures were not responsive as regards this effect”.
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References
Parmentier, R., and Dustin, P., Nature, 161, 527 (1948).
Parmentier, R., Nature, 171, 1029 (1953).
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ROSIN, A., DOLJANSKI, F. Effect of Hydroquinone on Mitosis. Nature 172, 1151 (1953). https://doi.org/10.1038/1721151a0
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DOI: https://doi.org/10.1038/1721151a0
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