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Determination of Adrenalin and Noradrenalin in the Human Fœtal Adrenals and Aortic Bodies

Abstract

THE adrenalin content of the fœtal adrenals has been studied in experimental animals by biological and chemical methods to a relatively insignificant extent; corresponding studies on human material are scarce. Lelkes1 has shown by biological methods that as early as towards the end of the third fœtal month the human adrenal gland already contains adrenalin, and beginning with the fifth month it can also be demonstrated more abundantly in Zuckerkandl's body. The noradrenalin content of the human fœtus has scarcely been studied at all. Therefore, we have attempted to make a chemical determination of the noradrenalin and adrenalin in human fœtal adrenals and Zuckerkandl's body at different stages of the intrauterine period.

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References

  1. Lelkes, Z., Endokrinologie, 23, 259 (1941).

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  2. v. Euler, U. S., and Hamberg, U., Acta Physiol. Scand., 19, 74 and 207 (1949).

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  3. Niemineva, K., and Pekkarinen, A., Ann. Med. Exp. et Biol. Fenn., [30, 274 (1952)].

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NIEMINEVA, K., PEKKARINEN, A. Determination of Adrenalin and Noradrenalin in the Human Fœtal Adrenals and Aortic Bodies. Nature 171, 436–437 (1953). https://doi.org/10.1038/171436b0

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