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Effects of some Chelate Compounds upon the Formation in vitro of Melanin

Abstract

IT is said that cupric ions accelerate the autoxidation of 3,4-dihydroxyphenylalanine (dopa)1 and, on the other hand, that they combine with pterins, riboflavin, amino-acids and other organic substances to form chelate complexes2. We have therefore carried out some experiments to investigate the behaviour of metal-bound pterins and riboflavin in relation to the rate of oxidation of dihydroxyphenylalanine.

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References

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ISAKA, S., ISHIDA, S. Effects of some Chelate Compounds upon the Formation in vitro of Melanin. Nature 171, 303–304 (1953). https://doi.org/10.1038/171303a0

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