Abstract
IN an earlier publication1 we reported that vitamin B12 could not be replaced for Euglena gracilis var. bacillaris by vitamin-free casein hydrolysate, carbon-treated peptone, methionine, ascorbic acid, pteroylglutamic acid, a variety of purine and pyrimidine bases or by xanthopterin and a number of related compounds. Hutner et al.2 found thymidine to be ineffective. Vitamin B12a (hydroxocobalamin) was active1. We have examined a number of additional compounds for vitamin B12 activity on Euglena.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Robbins, W. J., Hervey, A., and Stebbins, M. E., Bull. Torrey Bot. Club, 77, 423 (1950).
Hutner, S. H., Provasoli, L., Stokstad, E. L. R., Hoffmann, C. E., Belt, M., Franklin, A. L., and Jukes, T. H., Proc. Soc. Exp. Biol. and Med., 70, 118 (1949).
Emerson, G., Holly, F. W., Shunk, C. H., Brink, N. G., and Folkers, K., J. Amer. Chem. Soc., 73, 1069 (1951).
Robbins, W. J., Hervey, A., and Stebbins, M. E., Bull. Torrey Bot. Club, 78, 363 (1951).
Woolley, D. W., Proc. Soc. Exp. Biol. and Med., 75, 745 (1950); J. Exp. Med., 93, 13 (1951).
Cooley, G., Ellis, B., Petrow, V., Beaven, G. H., Holiday, E. R., and Johnson, E. A., J. Pharm. and Pharmacol., 3, 271 (1951).
Pfiffner, J. J., Calkins, D. G., Peterson, R. C., Bird, O. D., McGlohon, V., and Stipek, R. W., Amer. Chem. Soc., Abstracts of 120th Meeting 1951, 22C (1951).
Dion, H. W., Calkins, D. G., and Pfiffner, J. J., J. Amer. Chem. Soc., 74, 1108 (1952).
From correspondence with Dr. J. J. Pfiffner.
Lewis, U. J., Tappan, D. V., and Elvehjem, C. A., J. Biol. Chem., 194, 539 (1952).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
ROBBINS, W., HERVEY, A. & STEBBINS, M. Specificity of Vitamin B12 for Euglena. Nature 170, 845–846 (1952). https://doi.org/10.1038/170845b0
Issue Date:
DOI: https://doi.org/10.1038/170845b0
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.