Abstract
A RECENT joint communication from workers at Cambridge and Leeds1 reported that glycine-α-amino groups are liberated in the fibrinogen molecule when it is converted into fibrin, and strongly emphasized the proteolytic nature of the clotting reaction. The present communication is to report also that non-protein nitrogen is liberated through the splitting off, at the same time, of a portion of the fibrinogen molecule.
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References
Bailey, K., Bettelheim, F. R., Lorand, L., and Middlebrook, W. R., Nature, 167, 233 (1951).
Jaques, L. B., Biochem. J., 32, 1181 (1938).
Lorand, L., Nature, 166, 694 (1950).
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LORAND, L. ‘Fibrino-Peptide’: New Aspects of the Fibrinogen–Fibrin Transformation. Nature 167, 992–993 (1951). https://doi.org/10.1038/167992a0
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DOI: https://doi.org/10.1038/167992a0
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