Abstract
BOVET et al.1 examined the curarizing properties of a large number of bis-quaternary ammonium salts. More recently, they have found that in the group of bis-choline esters of aliphatic dicarboxylic acids, the succinyl esters provide the most powerful members of the series2.
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References
Bovet, Courvoisier, Ducrot and Horclois, C.R. Acad. Sci., Paris, 223, 597 (1946). Bovet, Depierre and deLestrange, ibid., 225, 74 (1947).
Bovet, Bovet-Nitti, Guarino, Longo and Marotta, Rend. 1st Sup. San., 12, 106 (1949).
Simonart, J. Pharmacol., 46, 157 (1932). deLestrange and Lévy, Bull. Sci. Pharmacol., 36, 353 (1929).
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VANDERHAEGHE, H. Curare-like Activity of some bis-Choline Derivatives. Nature 167, 527–528 (1951). https://doi.org/10.1038/167527a0
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DOI: https://doi.org/10.1038/167527a0
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