Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

A Synthetic Amphoteric Polypeptide

Abstract

THE amphoteric ionic behaviour, one of the characteristics of proteins, has been considered to be due to the presence of the amino- and the carboxyl-groups in the side-chains of the polypeptide chain. Since the natural proteins consist of various amino-acids, and their structures are very complex, it is desirable, in order to study this particular property, to prepare an ampholyte of a simple structure containing many amino- and carboxyl-groups.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Alfrey, T., Morawetz, jun., H., Fitzgerald, Z. B., and Fuoss, R. H., J. Amer. Chem. Soc., 72, 1864 (1950).

    Article  CAS  Google Scholar 

  2. Tani, H., and Noguchi, J. (unpublished).

  3. Bergamann, M., Zervas, L., and Ross, W. E., J. Biol. Chem., 111, 245 (1935).

    Google Scholar 

  4. Hanby, W. H., Weley, S. G., and Watson, S., Nature, 161, 132 (1948).

    Article  ADS  CAS  Google Scholar 

  5. Katchalski, E., Grossfeld, I., and Frankel, M., J. Amer. Chem. Soc., 70, 2094 (1948).

    Article  CAS  Google Scholar 

  6. Noma, K., and Tsuchida, T., J. High Polymers, Japan, 6, 282 (1949) have shown that ethyl phenylacetate is a good, solvent in the polymerization of the compound (I).

    CAS  Google Scholar 

  7. The osmotic pressure was determined by the simplified dynamic method. (cf. Mesituka, G., J. High Polymers, Japan, 6, 305 (1949).)

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

AKABORI, S., TANI, H. & NOGUCHI, J. A Synthetic Amphoteric Polypeptide. Nature 167, 159–160 (1951). https://doi.org/10.1038/167159a0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/167159a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing