Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Variation of the Somatic Chromosome Number in Man

Abstract

THE necessity of stressing the importance of chromosomes in the organization of plants and animals, and their decisive role in inheritance, caused O. Hertwig in 1918 to formulate the ‘law of constancy of chromosome number’, which implies that all cells of a given organism contain the same somatic number of chromosomes. A great number of observations have, however, shown that this concept is in need of revision. Especially in insects1,2 and in plants3, it has been established that certain cells and even whole tissues may represent different degrees of polyploidy.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Geitler, L., “Chromosomenbau” (Berlin, 1938).

    Google Scholar 

  2. Oksala, T., Hereditas, 25, 132 (1939).

    Article  Google Scholar 

  3. Huskins, C. L., Proc. 8th Internat. Congress Genetics, 274 (1948).

  4. Karplus, H., Z. Zellf., 10, 38 (1930).

    Article  Google Scholar 

  5. Andres, A. H., and Jiv, B. V., Cytologia, 7, 371 (1936).

    Article  Google Scholar 

  6. Kemp, T., Z. Zellf., 11, 429 (1930).

    Article  Google Scholar 

  7. Timonen, S., and Therman, E., Cancer Research, 10, 431 (1950).

    CAS  PubMed  Google Scholar 

  8. Therman, E., and Timonen, S., Hereditas (in the press).

  9. Timonen, S., Acta Obstetr. Scand., 31, Supp. 2, 1 (1951).

    Google Scholar 

  10. Therman, E., and Timonen, S., Hereditas (in the press).

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

TIMONEN, S., THERMAN, E. Variation of the Somatic Chromosome Number in Man. Nature 166, 995–996 (1950). https://doi.org/10.1038/166995a0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/166995a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing