Abstract
THE pathway by which the hypothalamus influences the secretion of the anterior pituitary gland has been the subject of much research. The possibility that the hypophysial portal vessels may form part of this pathway has been discussed1, and the anatomy of these structures in the rat and other forms has been described. In 1949, Harris2 observed that regeneration of the hypophysial portal vessels in the rat may follow section of the pituitary stalk, and later3 that post-operative return of reproductive activity can be correlated with such regeneration. In this work the hypophysial stalk was exposed by the sub-temporal route and either cut with a knife or torn with a hook. In the literature, accounts of stalk section made by a variety of methods show divergent results. Since the conditions for a regeneration of the portal vessels may vary according to the method used for severing the hypothalamo-hypophysial connexions, we have investigated the regenerative capacity of these vessels in different circumstances.
Similar content being viewed by others
Article PDF
References
Harris, G. W., Physiol. Rev., 28, 139 (1948).
Harris, G. W., Nature, 163, 70 (1949).
Harris, G. W., J. Endocrinol., 6, xviii (1949a).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
HARRIS, G., JACOBSOHN, D. Proliferative Capacity of the Hypophysial Portal Vessels. Nature 165, 854 (1950). https://doi.org/10.1038/165854a0
Issue Date:
DOI: https://doi.org/10.1038/165854a0
This article is cited by
-
Facteurs humoraux et nerveux de la r�ponse hypophyso-surr�nalienne au stress
Acta Neurovegetativa (1952)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.