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Comparison of Hydrophilic and Lipophilic Properties of Sera

Abstract

THERE is a constant exchange of salts, water, non-electrolytes such as sugars and also substances with lipoid solubility between the blood plasma and the reticulo-endothelial system (liver, spleen). The binding power of the serum proteins for these various substances is different, and the transport capacity for any one category varies with the protein composition of the serum. If superimposed processes, like local variations of concentration and variation in the thickness of the epithelial layer, are neglected, the process can be compared with the elution of absorbed substances in a chromatographic pile.

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WUNDERLY, C. Comparison of Hydrophilic and Lipophilic Properties of Sera. Nature 165, 850–851 (1950). https://doi.org/10.1038/165850a0

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