Abstract
THE increased consumption of oxygen produced by thyroxine was investigated with white mice desensitized with histamine. We have published elsewhere an account of the mechanism of histamine desensitization (which is, in fact, a decreased sensitivity to histamine), and the test which was used for controlling the establishment of desensitization1,2,3. The oxygen consumption was recorded on an Issekutz apparatus4 at 30° C. The experiments were performed on forty white mice, with forty controls, between the weights of 19 and 22 gm.
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References
Fabinyi, M., and Szebehely, J., Arch. Int. Pharmacodyn., 75, 402 (1948).
Fabinyi, M., and Szebehely, J., Schweiz. Med. Wschr., 79, 299 (1949).
Fabinyi, M., and Szebehely, J., Acta Allerg., 2, 233 (1949).
Issekutz, B., Schmiedebergs Arch., 199, 306 (1942).
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FABINYI-SZEBEHELY, M., GYERMEK, L. & SZEBEHELY, J. Effect of Histamine Desensitization upon Thyroxine Sensitivity. Nature 165, 155–156 (1950). https://doi.org/10.1038/165155b0
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DOI: https://doi.org/10.1038/165155b0
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