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Anterior Pituitary Explants of Infantile Rats Grafted in the Anterior Eye Chamber of Hypophysectomized Hosts

Abstract

IN an earlier communication1, we have shown that hypophysectomized rats, irrespective of the length of time during which they were hypophysectomized, responded to pieces of the anterior pituitary introduced in the anterior chamber of the eye by a prompt resumption of growth. Some such grafted pieces of the anterior pituitary survived for periods of sixteen months, showing signs of their activity, as reflected by the growth of the host animal, during all that time. Two animals with sixteen-months old grafts are still alive and still growing.

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References

  1. Martinovitch, P. N., “Functional Pituitary Grafts in the Rat” (published in reprint form by the Serbian Academy of Science, June 20, 1949).

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  2. Martinovitch, P. N., Medicinski pregled, 7 (1940).

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MARTINOVITCH, P. Anterior Pituitary Explants of Infantile Rats Grafted in the Anterior Eye Chamber of Hypophysectomized Hosts. Nature 165, 33–34 (1950). https://doi.org/10.1038/165033b0

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  • DOI: https://doi.org/10.1038/165033b0

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