Abstract
BOYD1 suggested that the closeness of the alpha and beta optima is a property of antitoxic sera due to the narrowness of the flocculation zone in such systems ("extreme H type"). Boyd and Purnell2 gave theoretical reasons why the two optima cannot coincide and suggested that the true optimum, designated epsilon, lies between them.
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References
Boyd, W. C., J. Exp. Med., 74, 369 (1941).
Boyd, W. C., and Purnell, M. A., J. Exp. Med., 80, 289 (1944).
Miles, A. A., Brit. J. Exp. Path., 14, 43 (1933).
Svedberg, T., and Hedenius, A., Biol. Bull., 66, 191 (1934).
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ELEK, S., LEVY, E. Flocculation Optima in Diphtheria Toxoid-Antitoxin Systems. Nature 164, 353–354 (1949). https://doi.org/10.1038/164353a0
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DOI: https://doi.org/10.1038/164353a0
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