Abstract
THE red cell agglutination test1 has proved an invaluable means for the rapid assay of certain viruses, namely, influenza, Newcastle disease, fowl plague and mumps, and furthermore the red cell – virus system is serving as an experimental model for investigating some of the factors involved when a virus attacks a susceptible cell2,3. We have for some time been interested in the possibility of gaining direct optical evidence on the mechanism of the process. The membranes of the laked red cells can be successfully photographed in the electron microscope (Wolpers4, Dawson and MacFarlane5), and this enables an optical study of the interaction of viruses with such membranes to be made.
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References
Hirst, G. K., Science, 94, 22 (1941).
Hirst, G. K., J. Exp. Med., 78, 99 (1943).
Burnet, F. M., Lancet, i, 7 (1948).
Wolpers, C., Naturwiss., 29, 416 (1941).
Dawson, I. M., and MacFarlane, A. S. (unpublished).
Dounce, A. L., and Lan, T. H., Science, 97, 584 (1943).
Heinmets, F., J. Bact., 55, 823 (1948).
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DAWSON, I., ELFORD, W. Electron Microscope Studies on the Interaction of Certain Viruses with Fowl Red Cell Membranes. Nature 163, 63–64 (1949). https://doi.org/10.1038/163063b0
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DOI: https://doi.org/10.1038/163063b0
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