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Excretion of D-Pyrrolidone Carboxylic Acid by Rat and Dog Fed with Tumour Proteins

Nature volume 162, pages 732–733 (1948)Cite this article

Abstract

THERE has been much controversy about our claim1 that D-glutamic acid is a constituent of tumour proteins. Many authors were unable to confirm our results, and in their opinion the D-form which we isolated from malignant tumours Was formed by partial racemization in vitro during the hydrolysis with hydrochloric acid. An explanation of these contradictory results will be given in future publications. Here we wish to record further evidence for the correctness of our views.

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References

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Authors and Affiliations

  1. Organisch-chemisch Laboratorium der Rijksuniversiteit, Utrecht

    F. KÖGL, T. J. BARENDREGT & A. J. KLEIN

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  1. F. KÖGL
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  2. T. J. BARENDREGT
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  3. A. J. KLEIN
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KÖGL, F., BARENDREGT, T. & KLEIN, A. Excretion of D-Pyrrolidone Carboxylic Acid by Rat and Dog Fed with Tumour Proteins. Nature 162, 732–733 (1948). https://doi.org/10.1038/162732b0

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