Abstract
THE succinoxidase content of experimental tumours of various origins, as well as of spontaneous tumours, has been found to be low1–6. In agreement with these findings in experiments conducted here, a low succinoxidase activity was found in hepatic tumours produced by feeding p-dimethylaminoazobenzene7. In a series of experiments, however, the completion of which has been delayed for technical reasons, it was observed that hepatic tumours produced by feeding 2-acetaminofluorene have an exceptional position in so far that the succinoxidase content of these tumours is about the same as, or but very slightly lower than, that of livers from normal rats on the same diet without the carcinogenic compound.
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HOCH-LIGETI, C. Succinoxidase Activity of Hepatic Tumours Produced in Rats by Feeding 2-Acetaminofluorene. Nature 159, 780 (1947). https://doi.org/10.1038/159780a0
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DOI: https://doi.org/10.1038/159780a0
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