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Use of Trypsin in the Detection of Incomplete Anti-Rh Antibodies

Nature volume 159, pages 779–780 (1947)Cite this article

Abstract

IN an attempt to define the properties of the enzyme present in the filtrate of a culture of vibrio cholera, which causes cells sensitized with an 'incomplete' anti-Rh antibody to agglutinate1, cultures of other organisms and pure enzyme preparations have been tested. During this investigation trypsin has been found to cause agglutination of cells sensitized with an 'incomplete' antibody, and also to enhance the specific agglutination of other hæmagglutinins in the absence of any detectable antibody of the 'incomplete' type.

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References

  1. Pickles, M. M., Nature, 158, 880 (1946).

    Article  ADS  CAS  PubMed  Google Scholar 

  2. Delezene, C., and Pozerski, E., C.R. Soc. Biol. Paris, 55, 327 (1903).

    Google Scholar 

  3. Weiner, A. S., Proc. Soc. Biol. Exp. and Med., 56, 173 (1944).

    Article  Google Scholar 

  4. Coombs, R. R. A., Mourant, A. E., and Race, R. R., Brit. J. Exp. Path., 26, 255 (1945).

    CAS  PubMed  PubMed Central  Google Scholar 

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Authors and Affiliations

  1. Division of Laboratories, Radcliffe Infirmary, Oxford

    J. A. MORTON & M. M. PICKLES

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  1. J. A. MORTON
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  2. M. M. PICKLES
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MORTON, J., PICKLES, M. Use of Trypsin in the Detection of Incomplete Anti-Rh Antibodies. Nature 159, 779–780 (1947). https://doi.org/10.1038/159779b0

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