Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

A Quantitative Study of the Toxic Action of Quinones on Planaria gonocephala

Abstract

THE purpose of the experiments to be described in this paper have been: (1) to continue studies on the mechanism of the antibiotic and toxic effects of certain quinone derivatives1; and (2) to extend earlier investigations2 and to study the so-called axial gradients in a quantitative way. Planaria gonocephala was chosen as a suitable model organism for both purposes. Eleven different quinone derivatives have been tested.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Hoffmann-Ostenhof, O., and Lee, W. H., Monatsh. Chem. (Vienna), 76, 180 (1946). Hoffmann-Ostenhof, O., and Biach, E., Monatsh. Chem. (in the press). Experientia (Basle) (in the press).

    Article  CAS  Google Scholar 

  2. v. Bertalanffy, L., Biologia Generalis (Vienna), 15, 295 (1942). Cf. also v. Bertalanffy, L., "Theoretische Biologie", 2 (Berlin, 1942).

    Google Scholar 

  3. Cooper, E. A., Biochem. J., 7, 186 (1913). Cooper, E. A., and Nicholas, S. D., J. Soc. Chem. Ind., 46, T59 (1927). Oxford, A. E., and Raistrick, H., Chem. Ind., 61, 128 (1942). Oxford, A. E., Chem. Ind., 61, 189 (1942).

    Article  CAS  Google Scholar 

  4. Wallenfels, K., Chemie (Berlin), 58, 1 (1945).

    CAS  Google Scholar 

  5. Herzog, R. O., and Betzel, R., Hoppe-Seylers Z. physiol. Chem., 74, 221 (1911). Cf. also Clark, A. J., "The Mode of Action of Drugs on Cells" (London, 1933).

    Google Scholar 

  6. For example, Child, C. M., Protoplasma (Berlin), 5, 447 (1929).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

V. BERTALANFFY, L., HOFFMAN-OSTENHOF, O. & SCHREIER, O. A Quantitative Study of the Toxic Action of Quinones on Planaria gonocephala. Nature 158, 948–949 (1946). https://doi.org/10.1038/158948a0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/158948a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing