Abstract
ELECTRON micrographs of bacteria1 and of virus particles2 covered with an obliquely deposited metallic film have a three-dimensional appearance that brings out clearly the shapes of these objects. The visibility of small objects appearing in these preparations has been so greatly enhanced by the shadowing technique3 that we have been led to apply it to the photography of the elementary particles, or molecules, of a number of proteins and high polymeric substances. The present communication describes such experiments carried out on a hæmocyanin.
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References
Williams, R. C., and Wyckoff, R. W. G., Proc. Exp. Biol. Med., in the press.
Williams, R. C., and Wyckoff, R. W. G., Proc. Exp. Biol. Med., 58, 265 (1945).
Williams, R. C., and Wyckoff, R. W. G., J. Appl. Phys., 15, 712 (1944).
Stanley, W. M., and Anderson, T. F., J. Biol. Chem., 146, 25 (1942).
Williams, R. C., and Wyckoff, R. W. G., Science, in the press.
See, for example, Schaefer, V. J., and Harker, D., J. Appl. Phys., 13, 427 (1942).
Eriksson-Quensel, I-B., and Svedberg, T., Biol. Bull., 71, 498 (1936).
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WILLIAMS, R., WYCKOFF, R. Electron Shadow-Micrographs of Hæmocyanin Molecules. Nature 156, 68–70 (1945). https://doi.org/10.1038/156068a0
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DOI: https://doi.org/10.1038/156068a0
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