Abstract
SEVERAL attempts by different authors1 to propagate human poliomyelitis virus in the developing chick embryo have been entirely negative. In these experiments the technique employed was that elaborated by Burnet, the eggs being inoculated on the 10–12th day of incubation. Recently, however, I reported2 successful transfer to, and serial passage n, chick embryos of mouse poliomyelitis virus (Theiler's virus). In conformity with the observation by Kligler and Bernkopf3 on rabies virus, it was found that only young embryos—5–7 days old—were susceptible to infection. The virus was restricted to the central nervous system, and no lesions were detectable.
Similar content being viewed by others
Article PDF
References
Burnet, F. M., Med. J. Austral., 1, 46 (1935). Gavrilov, W., and Fester, A., Arch. ges. Virusforsch., 1, 404 (1940).
Gard, S., Acta Med. Scand., Suppl. 143 (1943).
Kligler, I. J., and Bernkopf, H., NATURE, 143, 899 (1939).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
GARD, S. Human Poliomyelitis in the Developing Chick Embryo. Nature 152, 660 (1943). https://doi.org/10.1038/152660a0
Issue Date:
DOI: https://doi.org/10.1038/152660a0
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.