Abstract
AN interesting point in connexion with hæmolysis is the variation in the resistance of erythrocytes obtained from the different species of animals towards a particular hæmolysin. It was Rywosch1 who first attempted a sort of generalization in this connexion by pointing out that the series obtained by writing down the names of common laboratory animals according to the order of resistance of their erythrocytes to hypotonic saline is just the reverse of that obtained by ranging them according to their resistance to saponin hæmolysis. Various suggestions were put forward from time to time to explain this inverse relation, which suggested the possibility of the existence of some factor within the corpuscles which operated in a reverse manner with respect to the lysins concerned.
Similar content being viewed by others
Article PDF
References
Rywosch, Pflügers Arch., 116, 229 (1907).
Ponder and MacLachlan, Brit. J. Exp. Path., 8, 267 (1927).
Ponder, Salsow and Yeager, Biochem. J., 24, 805 (1930).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
ROY, A. Fragility of Erythrocytes in Hypotonic Saline. Nature 152, 599 (1943). https://doi.org/10.1038/152599b0
Issue Date:
DOI: https://doi.org/10.1038/152599b0
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.