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Sulphanilamides and Experimental Tuberculosis

Abstract

A NUMBER of workers have claimed that sulphanilamide 1, sulphapyridine2, prontosil soluble 3, and sulphathiazole4 in high concentrations may modify the course of experimental tuberculosis in guinea pigs. Promin, p,p'-diaminodiphenylsulphone-N,N'-didextrose sulphonate, has also been found effective in animal experiments5. However, no positive clinical results have been secured with the first-mentioned sulphanilamides, while promin is at present being tested.

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SJÖGREN, B. Sulphanilamides and Experimental Tuberculosis. Nature 150, 431–432 (1942). https://doi.org/10.1038/150431b0

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