Abstract
RECENT work has shown that the local application of sodium sulphacetamide can control the development of experimental corneal ulcers in rabbits (Robson and Scott1). This sulphonamide is also being used clinically in concentrations up to 30 per cent for the treatment of various ocular infections, and especially of hypopyon ulcers, and it became of interest to determine the concentration attained in the various ocular tissues, when solutions are applied locally to the conjunctival sac.
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References
Robson, J. M., and Scott, G. I., NATURE, 148, 167 (1941).
Marshall, E. K., and Litchfield, J. T., Science, 88, 85 (1938).
P'an, S. Y., Proc. Soc. Exp. Biol., 46, 31 (1941).
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ROBSON, J., TEBRICH, W. Penetration of a Water–soluble Sulphonamide, Sodium Sulphacetamide (Albucid–soluble) into the Eyes of Rabbits. Nature 148, 695–696 (1941). https://doi.org/10.1038/148695c0
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DOI: https://doi.org/10.1038/148695c0
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