Abstract
IT has long been known that vitamin D exerts a profound influence upon the calcification of developing teeth. The action of this vitamin in massive doses upon the persistently growing incisor of the rat has been described by Schour and Ham1 in the normal animal and by Schour, Tweedy, Chandler and Engel2 after parathyroidectomy. In both cases the change in the dentin consisted in essentials of a hypocalcified stripe followed by a reactive hyper-calcified zone. It does not appear, however, that the reaction of the dentin has been followed in rachitic rats given curative doses of the vitamin.
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References
Schour, I., and Ham, A. W., Arch. Path., 17, 22 (1934).
Schour, I., Tweedy, W. R., Chandler, S. B., and Engel, M. B., Amer. J. Path., 13, 971 (1937).
Irving, J. T., J. Physiol., 99, 8 (1940).
Morgareide, K., and Manley, M. L., J. Nutrition, 18, 411 (1939).
Dyer, F. J., Quart. J. Pharm. Pharmacol., 4, 503 (1931).
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IRVING, J. Influence of Vitamin D upon the Incisor Teeth of Rachitic Rats. Nature 147, 608–609 (1941). https://doi.org/10.1038/147608a0
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DOI: https://doi.org/10.1038/147608a0
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