Abstract
OBJECTIONS have been raised against the use of radioactive indicators in physiology, suggesting two sources of error, namely, a discriminating effect for isotopic atoms, and a change in the behaviour of organic material through irradiation1. Although one has good theoretical reasons to believe that the radioactive tracer atoms and their non-active isotopes show the same physico-chemical behaviour2, and that effects of irradiation could be neglected so long as the specimens are not too active3, it has been emphasized2 that doubts about the tracer method can only be removed by experimental evidence.
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References
Barnett, A., Phys. Rev., 56, 963 (1939).
Crane, H. R., ibid., 56, 1234 (1939).
Mullins, Lorin J., ibid., 56, 1244 (1939), Hevesy, G., ibid., 57, 240 (1940).
Brewer, A. Keith, Ind. and Eng. Chem., 30, 893 (1938).
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Livingood, J. J., and Seaborg, G. T., Rev. Mod. Phys., 12, 30 (1940).
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BLÜH, O. Mixed Radioactive Indicators in Physiological Experiments. Nature 146, 233–234 (1940). https://doi.org/10.1038/146233a0
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DOI: https://doi.org/10.1038/146233a0
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