Abstract
IN the last resort, the degree of importance which is attached to the carcinogenic substances depends upon whether such compounds are concerned in the etiology of 'spontaneous' human cancer. Perhaps closely bound up with this question is another unsolved problem of outstanding importance, namely, the manner in which these compounds bring about a transformation of normal cells into malignant cells. At least until answers are forthcoming to these questions, the carcinogenic compounds will continue to furnish useful material for the experimental study of cancer. Industrial cancer, in its various forms, has stimulated the researches which have brought to light the cancer-producing properties of the various carcinogenic agents, and in the preparation of the present brief survey of these agents regard has been paid to the correlation of the various forms of industrial cancer with their causative compounds.
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COOK, J. Cancer-Producing Chemical Compounds. Nature 145, 335–338 (1940). https://doi.org/10.1038/145335a0
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DOI: https://doi.org/10.1038/145335a0
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