Abstract
A SHORT time ago, Prof. A. E. Braunstein1 discussed the specificity of the salicylaldehyde reaction proposed by Csonka for the determination of acetone and by Straub for the determination of pyruvic acid, and suggested that a positive reaction is obtained with all compounds containing a CH3CO group linked directly to a hydrogen or carbon atom, and that the reaction is negative with carbonyl compounds which do not contain the aforementioned grouping. The mechanism responsible for this range of specificity was stated to involve the possibility or otherwise of enolization ensuing in a strongly alkaline medium, leading to the formation of an enolate the colour of which was attributed to a cumulated double bond system.
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References
Braunstein, NATURE, 140, 427 (1937).
Borsche and Geyer, Annalen, 393, 49 (1912).
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THOMSON, T. Specificity of the Salicylaldehyde Reaction of Csonka-Straub. Nature 141, 917 (1938). https://doi.org/10.1038/141917a0
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DOI: https://doi.org/10.1038/141917a0
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