Abstract
A NUMBER of facts relating to proteins1 suggest that the polypeptides in native proteins are in a folded state2-3. The type of folding must be such as to imply the possibility of the regular and orderly arrangement of hundreds of amino acid residues, which to some extent at least is independent of the particular residues in question.
Article PDF
References
Pryde, ” Recent Advances in Biochemistry”. chap, i (1931); Langmuir, Schaefer and Wrinch, Science, 85, 76 (1937).
Astbury, NATURE, 132, 593 (1933). Koll. Z., 69, 340 (1934). Astbury and Street, NATURE, 126, 913 (1930). Phil. Trans. Roy. Soc., A, 230, 75 (1931).
Wrinch, NATURE, 137, 411: 138, 241: 138, 651 (1936). Proc. Roy. Soc., A, in the Press.
Astbury, J. Text. Inst., 17, P. 281 (1936). NATURE, 137, 803 (1936). Chem. Weekblad, 33, 778 (1936).
Jordan Lloyd, Biol. Rev., 7, 254 (1932). Mirsky and Pauling, Proc. Nat. Acad. Sci., 22, 439 (1936). Wrinch and Jordan Lloyd, NATURE, 138, 758 (1936).
Svedberg et al., Koll. Z., 51, 10 (1930). Trans. Far. Soc., 26, 72 and 737 (1930). Science, 79, 327 (1934). Biol. Bull., 66, 191 (1934). Chem. Rev., 14, 1 (1935), and a series of papers in J. Amer. Chem. Soc., from 1929.
Dickinson and Raymond, J. Amer. Chem. Soc., 45, 22 (1923). Wyckoff and Corey, Z. Krist., 89, 426 (1934).
Andreini, Soc. Ital. d. Scienze, 14, 75 (1907).
Jordan Lloyd, Biochem. J., 14, 147 (1920); 21, 1352 (1927); 25, 1580 (1931). Biol. Rev., 8, 463 (1933).
Svedberg and Eriksson-Quensel, ” Tabulæ Biologicæ Periodicæ”, 5, 351 (1935–36).
Rights and permissions
About this article
Cite this article
Wrinch, D. The Cyclol Theory and the Globular Proteins. Nature 139, 972–973 (1937). https://doi.org/10.1038/139972a0
Published:
Issue Date:
DOI: https://doi.org/10.1038/139972a0
This article is cited by
-
A theoretical reappraisal of the cyclol hypothesis
Structural Chemistry (2012)
-
The fabric structure oe proteins with special reference to cytogenetics
Journal of Genetics (1940)
-
�ber den Aufbau der Eiwei�molek�le
Kolloid-Zeitschrift (1937)