Induction by Coagulated Organisers in the Chick Embryo

Abstract

IN a series of short communications, Bautzmann, Holtfreter, Spemann and Mangold¹ have recently reported the results of experiments in which they attempted to obtain typical organiser reactions (that is, the induction of a neural plate in the presumptive epidermis in Triton) by organisers which had been killed. Marx² had previously demonstrated that inductions could be performed by organisers which had been narcotised by trichlorbutyl alcohol to such an extent that they degenerated and were absorbed, while Spemann³ had obtained inductions by organisers which had been crushed, but not by those which had been frozen or dried.