Abstract
LONDON. Royal Society, Jan. 13.—F. W. R. Brambell, A. S. Parkes, and Una Fielding: Changes in the ovary of the mouse following exposure to X-rays. Part i. Irradiation at 3 weeks old. Degeneration occurred of all oocytes in the ovaries of 47 female mice, exposed to full sterility dose of X-rays at 3 weeks old. Membrana granulosa and theca interna, in those cases where differentiated, degenerate also. Finally old follicles are only represented by small cavities containing zona pellucida remnants. Simultaneously with these changes, old inter-follicular tissue atrophies, and germinal epithelium proliferates epithelial cords. In adult animals ovaries are composed almost entirely of this first proliferation. In many cases a second proliferation follows. This consists of small spherical or slightly elongated cords. These cords resemble so-called spermatic cords described in ovaries of inbred rabbits and of free-martin cattle. They also resemble structures described as anovular follicles. They have no effect on cestrous cycle.
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Societies and Academies. Nature 119, 144–147 (1927). https://doi.org/10.1038/119144b0
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DOI: https://doi.org/10.1038/119144b0