Abstract
Stroke is a very common cause of death and disability. Several lines of evidence point to stroke as a polygenic multifactoral phenotype and there are also a number of well studied single gene Mendelian stroke conditions. Rat models have identified several chromosomal sites linked to stroke, and this together with other background information provides a strategy for both cross-sectional and gene scanning approach to defining the genetics of human stroke.
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Carter, N. Genetics of stroke. J Hum Hypertens 11, 553–554 (1997). https://doi.org/10.1038/sj.jhh.1000486
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DOI: https://doi.org/10.1038/sj.jhh.1000486