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| Open AccessCatalytic specificity and crystal structure of cystathionine γ-lyase from Pseudomonas aeruginosa
- Marco Pedretti
- , Carmen Fernández-Rodríguez
- & Luis Alfonso Martínez-Cruz
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Article
| Open AccessIdentification and structural characterization of small molecule inhibitors of PINK1
- Shafqat Rasool
- , Tara Shomali
- & Jean-François Trempe
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Article
| Open AccessHigher level of physical activity reduces mental and neurological symptoms during and two years after COVID-19 infection in young women
- Johanna Takács
- , Darina Deák
- & Akos Koller
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| Open AccessTHOUSAND-GRAIN WEIGHT 6, which is an IAA-glucose hydrolase, preferentially recognizes the structure of the indole ring
- Tatsuki Akabane
- , Nobuhiro Suzuki
- & Naoki Hirotsu
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Article
| Open AccessStructure–function analysis of PorXFj, the PorX homolog from Flavobacterium johnsioniae, suggests a role of the CheY-like domain in type IX secretion motor activity
- Mariotte Zammit
- , Julia Bartoli
- & Philippe Leone
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| Open AccessStructural basis for the recognition of human hemoglobin by the heme-acquisition protein Shr from Streptococcus pyogenes
- Akinobu Senoo
- , Masato Hoshino
- & Kouhei Tsumoto
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| Open AccessStructural analysis of the Trypanosoma brucei EIF4E6/EIF4G5 complex reveals details of the interaction between unusual eIF4F subunits
- Renato Ferras Penteado
- , Renata Santana da Silva
- & Beatriz Gomes Guimarães
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Article
| Open AccessStructural basis for the activity and specificity of the immune checkpoint inhibitor lirilumab
- Nicholas Lorig-Roach
- , Nina M. Harpell
- & Rebecca M. DuBois
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| Open AccessStructural and biophysical comparisons of the pomalidomide- and CC-220-induced interactions of SALL4 with cereblon
- Xiaolei Ma
- , Barbara Leon
- & Charles A. Wartchow
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Article
| Open AccessPeriplasmic chitooligosaccharide-binding protein requires a three-domain organization for substrate translocation
- Takayuki Ohnuma
- , Jun Tsujii
- & Tamo Fukamizo
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Article
| Open AccessHis1-tagged DM or DDM detergent micelles are reversibly conjugated by nickel ions
- Mitra Lal
- , Ellen Wachtel
- & Guy Patchornik
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Article
| Open AccessCrystal structures and molecular dynamics simulations of a humanised antibody fragment at acidic to basic pH
- Jiazhi Tang
- , Cheng Zhang
- & Frank Kozielski
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Article
| Open AccessStructural and functional analysis of aquaporin-2 mutants involved in nephrogenic diabetes insipidus
- Carl Johan Hagströmer
- , Jonas Hyld Steffen
- & Susanna Törnroth-Horsefield
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Article
| Open AccessDiscovery and multimerization of cross-reactive single-domain antibodies against SARS-like viruses to enhance potency and address emerging SARS-CoV-2 variants
- Scott A. Hollingsworth
- , Cameron L. Noland
- & Kalyan Pande
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| Open AccessCrystal structure of domain of unknown function 507 (DUF507) reveals a new protein fold
- Cole E. McKay
- , Jianlin Cheng
- & John J. Tanner
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Article
| Open AccessCrystal structure of [1,2,4]triazolo[4,3-
b ]pyridazine derivatives as BRD4 bromodomain inhibitors and structure–activity relationship study- Jung-Hoon Kim
- , Navin Pandit
- & Byung Il Lee
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Article
| Open AccessAllopurinol non-covalently facilitates binding of unconventional peptides to HLA-B*58:01
- Xuelu Huan
- , Nicole Zhuo
- & Ee Chee Ren
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Article
| Open AccessRapid and efficient ambient temperature X-ray crystal structure determination at Turkish Light Source
- Mehmet Gul
- , Esra Ayan
- & Hasan DeMi̇rci̇
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Article
| Open AccessStructural characterisation of hemagglutinin from seven Influenza A H1N1 strains reveal diversity in the C05 antibody recognition site
- Seyed Mohammad Ghafoori
- , Gayle F. Petersen
- & Jade K. Forwood
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Article
| Open AccessStructural insights into thrombolytic activity of destabilase from medicinal leech
- Egor Marin
- , Daniil A. Kornilov
- & Valentin I. Borshchevskiy
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Article
| Open AccessThe thiolation of uridine 34 in tRNA, which controls protein translation, depends on a [4Fe-4S] cluster in the archaeum Methanococcus maripaludis
- Ornella Bimai
- , Pierre Legrand
- & Béatrice Golinelli-Pimpaneau
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Article
| Open AccessStructural and functional characterization of the catalytic domain of a cell-wall anchored bacterial lytic polysaccharide monooxygenase from Streptomyces coelicolor
- Amanda K. Votvik
- , Åsmund K. Røhr
- & Zarah Forsberg
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| Open AccessCharacterization of human oxidoreductases involved in aldehyde odorant metabolism
- Valentin Boichot
- , Franck Menetrier
- & Fabrice Neiers
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Article
| Open AccessStructural analysis of Plasmodium falciparum ookinete surface antigen Pfs28 relevant for malaria vaccine design
- Niharika Shukla
- , Wai Kwan Tang
- & Niraj H. Tolia
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Article
| Open AccessDiscovery and structural characterization of chicoric acid as a SARS-CoV-2 nucleocapsid protein ligand and RNA binding disruptor
- Gustavo Fernando Mercaldi
- , Eduardo Henrique Salviano Bezerra
- & Daniela Barretto Barbosa Trivella
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| Open AccessMapping periplasmic binding protein oligosaccharide recognition with neutron crystallography
- Shantanu Shukla
- , Dean A. Myles
- & Matthew J. Cuneo
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| Open AccessStructure of the pre-mRNA leakage 39-kDa protein reveals a single domain of integrated zf-C3HC and Rsm1 modules
- Hideharu Hashimoto
- , Daniel H. Ramirez
- & Erik W. Debler
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| Open AccessCell-free protein crystallization for nanocrystal structure determination
- Satoshi Abe
- , Junko Tanaka
- & Takafumi Ueno
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| Open AccessIdentification and structure-based drug design of cell-active inhibitors of interleukin 17A at a novel C-terminal site
- Eric R. Goedken
- , Maria A. Argiriadi
- & Chaohong Sun
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Article
| Open AccessStructural characterization of aspartate-semialdehyde dehydrogenase from Pseudomonas aeruginosa and Neisseria gonorrhoeae
- S. L. Teakel
- , J. W. Fairman
- & J. K. Forwood
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Article
| Open AccessVav2 is a novel APP-interacting protein that regulates APP protein level
- Youjia Zhang
- , Xiaxin Yang
- & Junfeng Wang
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Article
| Open AccessSubstrate size-dependent conformational changes of bacterial pectin-binding protein crucial for chemotaxis and assimilation
- Kotaro Anamizu
- , Ryuichi Takase
- & Wataru Hashimoto
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Article
| Open AccessStructural basis for the simultaneous recognition of NEMO and acceptor ubiquitin by the HOIP NZF1 domain
- Simin Rahighi
- , Mamta Iyer
- & Vincent Duong
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Article
| Open AccessHepatitis C virus NS3/4A inhibitors and other drug-like compounds as covalent binders of SARS-CoV-2 main protease
- Babak Andi
- , Desigan Kumaran
- & Sean McSweeney
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| Open AccessPurification, characterization, and preliminary serial crystallography diffraction advances structure determination of full-length human particulate guanylyl cyclase A receptor
- Shangji Zhang
- , Debra T. Hansen
- & Petra Fromme
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| Open AccessCrystal structure of potato 14-3-3 protein St14f revealed the importance of helix I in StFDL1 recognition
- Ken-ichi Harada
- , Kyoko Furuita
- & Chojiro Kojima
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Article
| Open AccessA unique peptide-based pharmacophore identifies an inhibitory compound against the A-subunit of Shiga toxin
- Miho Watanabe-Takahashi
- , Miki Senda
- & Kiyotaka Nishikawa
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Article
| Open AccessMethyl probes in proteins for determining ligand binding mode in weak protein–ligand complexes
- Biswaranjan Mohanty
- , Julien Orts
- & Martin J. Scanlon
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| Open AccessMechanisms of membrane protein crystallization in ‘bicelles’
- Tatiana N. Murugova
- , Oleksandr I. Ivankov
- & Valentin I. Gordeliy
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| Open AccessStructure of the glucosyltransferase domain of TcdA in complex with RhoA provides insights into substrate recognition
- Baohua Chen
- , Zheng Liu
- & Rongsheng Jin
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| Open AccessCrystal structure of ultra-humanized anti-pTau Fab reveals how germline substitutions humanize CDRs without loss of binding’
- Alette R. Brinth
- , Kristine Svenson
- & Matthew Lambert
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| Open AccessYeast-based directed-evolution for high-throughput structural stabilization of G protein-coupled receptors (GPCRs)
- M. Meltzer
- , T. Zvagelsky
- & Stanislav Engel
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| Open AccessFirst crystal structures of 1-deoxy-d-xylulose 5-phosphate synthase (DXPS) from Mycobacterium tuberculosis indicate a distinct mechanism of intermediate stabilization
- Robin M. Gierse
- , Rick Oerlemans
- & Matthew R. Groves
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| Open AccessAcoustic levitation and rotation of thin films and their application for room temperature protein crystallography
- Michal. W. Kepa
- , Takashi Tomizaki
- & Soichiro Tsujino
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Article
| Open AccessTunable x-ray free electron laser multi-pulses with nanosecond separation
- Franz-Josef Decker
- , Karl L. Bane
- & Alberto A. Lutman
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Article
| Open AccessNon contrast enhanced volumetric histology of blood clots through high resolution propagation-based X-ray microtomography
- Somayeh Saghamanesh
- , Daniela Dumitriu LaGrange
- & Robert Zboray
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Article
| Open AccessNon-covalent SARS-CoV-2 Mpro inhibitors developed from in silico screen hits
- Giacomo G. Rossetti
- , Marianna A. Ossorio
- & Thanos D. Halazonetis
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Article
| Open AccessStructure of Escherichia coli O157:H7 bacteriophage CBA120 tailspike protein 4 baseplate anchor and tailspike assembly domains (TSP4-N)
- Kinlin L. Chao
- , Xiaoran Shang
- & Osnat Herzberg
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