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| Open AccessMechanism study of tyrosine phosphatase shp-1 in inhibiting hepatocellular carcinoma progression by regulating the SHP2/GM-CSF pathway in TAMs
- Qiang Wei
- , ShuBin Luo
- & Gang He
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| Open AccessNOXA expression is downregulated in human breast cancer undergoing incomplete pathological response and senescence after neoadjuvant chemotherapy
- Sofian Al Shboul
- , Mohammed El-Sadoni
- & Tareq Saleh
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| Open AccessIncreased expression of HPV-E7 oncoprotein correlates with a reduced level of pRb proteins via high viral load in cervical cancer
- Bilal Ahmad Mir
- , Arif Ahmad
- & P. F. Rahaman
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| Open AccessRegulatory role of PI3K/Akt/WNK1 signal pathway in mouse model of bone cancer pain
- Xiao Fu
- , Yanhong Zhang
- & Rui Zhang
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| Open AccessCharacterizing the role of Phlda3 in the development of acute toxicity and malignant transformation of hematopoietic cells induced by total-body irradiation in mice
- Stephanie Hasapis
- , Isibel Caraballo
- & Chang-Lung Lee
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| Open AccessProteomic analysis of the effect of hemin in breast cancer
- G. P. Coló
- , K. Schweitzer
- & M. M. Facchinetti
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| Open AccessRNU12 inhibits gastric cancer progression via sponging miR-575 and targeting BLID
- Shaoli Wang
- , Changyan Zou
- & Xiandong Lin
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| Open AccessTumor suppressor DEAR1 regulates mammary epithelial cell fate and predicts early onset and metastasis in triple negative breast cancer
- Uyen Q. Le
- , Nanyue Chen
- & Ann McNeill Killary
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| Open AccessGlobal microRNA expression profile in laryngeal carcinoma unveils new prognostic biomarkers and novel insights into field cancerization
- Todor M. Popov
- , Gergana Stancheva
- & Diana P. Popova
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| Open Accessbrca2-mutant zebrafish exhibit context- and tissue-dependent alterations in cell phenotypes and response to injury
- Vassili A. Kouprianov
- , Aubrie A. Selmek
- & Heather R. Shive
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| Open AccessNovel ratio-metric features enable the identification of new driver genes across cancer types
- Malvika Sudhakar
- , Raghunathan Rengaswamy
- & Karthik Raman
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| Open AccessMachine learning random forest for predicting oncosomatic variant NGS analysis
- Eric Pellegrino
- , Coralie Jacques
- & L’Houcine Ouafik
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| Open AccessK15 promoter-driven enforced expression of NKIRAS exhibits tumor suppressive activity against the development of DMBA/TPA-induced skin tumors
- Kenji Tago
- , Satoshi Ohta
- & Ken Yanagisawa
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| Open AccessHeterozygous APC germline mutations impart predisposition to colorectal cancer
- Livia Preisler
- , Aline Habib
- & Dalit Ben-Yosef
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| Open AccessUpregulation of 5′-terminal oligopyrimidine mRNA translation upon loss of the ARF tumor suppressor
- Kyle A. Cottrell
- , Ryan C. Chiou
- & Jason D. Weber
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| Open AccessActivation of PAR2 by tissue factor induces the release of the PTEN from MAGI proteins and regulates PTEN and Akt activities
- Mohammad A. Mohammad
- , John Greenman
- & Camille Ettelaie
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| Open AccessSilencing of Testin expression is a frequent event in spontaneous lymphomas from Trp53-mutant mice
- Robert J. Weeks
- , Jackie L. Ludgate
- & Ian M. Morison
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| Open AccessUQCRH downregulation promotes Warburg effect in renal cell carcinoma cells
- Yanting Luo
- , Louise Medina Bengtsson
- & Xin Lu
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| Open AccessTransient binding and jumping dynamics of p53 along DNA revealed by sub-millisecond resolved single-molecule fluorescence tracking
- Dwiky Rendra Graha Subekti
- , Agato Murata
- & Kiyoto Kamagata
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| Open AccessTranscriptional mutagenesis dramatically alters genome-wide p53 transactivation landscape
- Shuo Liang
- , Monika Ezerskyte
- & Kristian Dreij
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| Open AccessInterleukin-1α associates with the tumor suppressor p53 following DNA damage
- J. Novak
- , B. Zamostna
- & M. Pospisek
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| Open AccessUnprovoked Stabilization and Nuclear Accumulation of the Naked Mole-Rat p53 Protein
- Marian M. Deuker
- , Kaitlyn N. Lewis
- & Jeff Settleman
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| Open AccessSimultaneous Inhibition of Glycolysis and Oxidative Phosphorylation Triggers a Multi-Fold Increase in Secretion of Exosomes: Possible Role of 2′,3′-cAMP
- Nils Ludwig
- , Saigopalakrishna S. Yerneni
- & Theresa L. Whiteside
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| Open AccessSoyasapogenol-A targets CARF and results in suppression of tumor growth and metastasis in p53 compromised cancer cells
- Amr Omar
- , Rajkumar Singh Kalra
- & Renu Wadhwa
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| Open AccessMonoamine oxidase A is down-regulated in EBV-associated nasopharyngeal carcinoma
- Hui Min Lee
- , Alice Pei Eal Sia
- & Lee Fah Yap
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| Open AccessHereditary Trichilemmal Cysts are Caused by Two Hits to the Same Copy of the Phospholipase C Delta 1 Gene (PLCD1)
- Michael S. Kolodney
- , Garrett C. Coman
- & Joanna A. Kolodney
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| Open AccessCombination therapy with mTOR kinase inhibitor and dasatinib as a novel therapeutic strategy for vestibular schwannoma
- Jessica E. Sagers
- , Roberta L. Beauchamp
- & Konstantina M. Stankovic
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| Open AccessInhibition of TGF-β signalling in combination with nal-IRI plus 5-Fluorouracil/Leucovorin suppresses invasion and prolongs survival in pancreatic tumour mouse models
- Eunji Hong
- , Sujin Park
- & Seong-Jin Kim
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| Open AccessPDCD4 controls the G1/S-phase transition in a telomerase-immortalized epithelial cell line and affects the expression level and translation of multiple mRNAs
- Astrid Haas
- , Benedikt S. Nilges
- & Karl-Heinz Klempnauer
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| Open Accessp53 dynamics in single cells are temperature-sensitive
- Marcel Jentsch
- , Petra Snyder
- & Alexander Loewer
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| Open AccessPifithrin-α alters p53 post-translational modifications pattern and differentially inhibits p53 target genes
- Jiawei Zhu
- , Madhurendra Singh
- & Sylvain Peuget
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| Open AccessSilencing of SENP2 in Multiple Myeloma Induces Bortezomib Resistance by Activating NF-κB Through the Modulation of IκBα Sumoylation
- Hongyi Xie
- , Yuanliang Gu
- & Peng Shu
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| Open AccessCompletion of BAX recruitment correlates with mitochondrial fission during apoptosis
- M. E. Maes
- , J. A. Grosser
- & R. W. Nickells
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| Open AccessCytosolic 10-formyltetrahydrofolate dehydrogenase regulates glycine metabolism in mouse liver
- Natalia I. Krupenko
- , Jaspreet Sharma
- & Sergey A. Krupenko
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| Open AccessA novel form of Deleted in breast cancer 1 (DBC1) lacking the N-terminal domain does not bind SIRT1 and is dynamically regulated in vivo
- Leonardo Santos
- , Laura Colman
- & Carlos Escande
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| Open AccessParadoxical epigenetic regulation of XAF1 mediates plasticity towards adaptive resistance evolution in MGMT-methylated glioblastoma
- Qiong Wu
- , Anders E. Berglund
- & Arnold B. Etame
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| Open AccessNb-induced stabilisation of p53 in HPV-infected cells
- Anneleen Steels
- , Laura Vannevel
- & Jan Gettemans
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| Open AccessPaired Box-1 (PAX1) Activates Multiple Phosphatases and Inhibits Kinase Cascades in Cervical Cancer
- Po-Hsuan Su
- , Hung-Cheng Lai
- & Cheng-Chang Chang
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| Open AccessUPF1 inhibits the hepatocellular carcinoma progression by targeting long non-coding RNA UCA1
- Yongli Zhou
- , Yandong Li
- & Liqiao Ge
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| Open AccessA novel regulatory circuit between p53 and GFI1 controls induction of apoptosis in T cells
- Charles Vadnais
- , Riyan Chen
- & Tarik Möröy
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| Open AccessEstrogen receptor beta enhances chemotherapy response of GBM cells by down regulating DNA damage response pathways
- Mei Zhou
- , Gangadhara R. Sareddy
- & Ratna K. Vadlamudi
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| Open AccessIdentification of a Novel Anti-cancer Protein, FIP-bbo, from Botryobasidium botryosum and Protein Structure Analysis using Molecular Dynamic Simulation
- Ying Wang
- , Ying Nv Gao
- & Da Peng Bao
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| Open AccessNew type of interaction between the SARAH domain of the tumour suppressor RASSF1A and its mitotic kinase Aurora A
- T. Szimler
- , É. Gráczer
- & M. Vas
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| Open AccessInfluence of p53 Isoform Expression on Survival in High-Grade Serous Ovarian Cancers
- Katharina Bischof
- , Stian Knappskog
- & Line Bjorge
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| Open AccessDeveloping a novel FRET assay, targeting the binding between Antizyme-AZIN
- Aram Ghalali
- , James M. Rice
- & Michael S. Rogers
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| Open AccessClinicopathological correlation of ARID1A status with HDAC6 and its related factors in ovarian clear cell carcinoma
- Mitsutake Yano
- , Tomomi Katoh
- & Masanori Yasuda
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| Open AccessInduction of GNMT by 1,2,3,4,6-penta-O-galloyl-beta-D-glucopyranoside through proteasome-independent MYC downregulation in hepatocellular carcinoma
- Rajni Kant
- , Chia-Hung Yen
- & Yi-Ming Arthur Chen
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| Open AccessSynergistic activation of the NEU4 promoter by p73 and AP2 in colon cancer cells
- Bi-He Cai
- , Po-Han Wu
- & Reiji Kannagi
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| Open AccessIdentification and Characterization of USP7 Targets in Cancer Cells
- Anna Georges
- , Edyta Marcon
- & Lori Frappier