Featured
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Article |
Cortical responses to touch reflect subcortical integration of LTMR signals
Genetic manipulation of skin peripheral sensory neurons in mice shows that cortical neuron responses to touch reflect subcortical mixing of signals from both rapidly adapting and slowly adapting low-threshold mechanoreceptors.
- Alan J. Emanuel
- , Brendan P. Lehnert
- & David D. Ginty
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Article |
Cortical direction selectivity emerges at convergence of thalamic synapses
Direction selectivity emerges de novo in layer 4 neurons of primary visual cortex through the convergence of synaptic inputs from thalamic neurons that respond with distinct time courses to visual stimuli in distinct locations.
- Anthony D. Lien
- & Massimo Scanziani
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Article |
A midline thalamic circuit determines reactions to visual threat
Separate outputs of the ventral midline thalamus comprise neural circuits that determine avoidance-based or confrontational responses to visual threat.
- Lindsey D. Salay
- , Nao Ishiko
- & Andrew D. Huberman
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Article |
Principles underlying sensory map topography in primary visual cortex
Recordings from cat visual cortex show that the cortical maps for stimulus orientation, direction and retinal disparity depend on an organization in which thalamic axons with similar retinotopy and light/dark responses are clustered together in the cortex.
- Jens Kremkow
- , Jianzhong Jin
- & Jose M. Alonso
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Letter |
Thalamic control of sensory selection in divided attention
The authors trained mice to attend to or suppress vision based on behavioral context and show, through novel and established techniques, that changes in visual gain rely on tunable feedforward inhibition of visual thalamus via innervating thalamic reticular neurons; these findings introduce a subcortical model of attention in which modality-specific thalamic reticular subnetworks mediate top-down and context-dependent control of sensory selection.
- Ralf D. Wimmer
- , L. Ian Schmitt
- & Michael M. Halassa
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Research Highlights |
Neuroscience: Dark migraine relief