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| Open AccessMyristoylated, alanine-rich C-kinase substrate (MARCKS) regulates toll-like receptor 4 signaling in macrophages
- Jiraphorn Issara-Amphorn
- , Virginie H. Sjoelund
- & Aleksandra Nita-Lazar
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| Open AccessSimultaneous reduction of all ORMDL proteins decreases the threshold of mast cell activation
- Livia Demkova
- , Viktor Bugajev
- & Ivana Halova
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| Open AccessIn vitro kinase assay reveals ADP-heptose-dependent ALPK1 autophosphorylation and altered kinase activity of disease-associated ALPK1 mutants
- Diego García-Weber
- , Anne-Sophie Dangeard
- & Cécile Arrieumerlou
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| Open AccessGRB2 dimerization mediated by SH2 domain-swapping is critical for T cell signaling and cytokine production
- Aline Sandouk
- , Zhen Xu
- & Jon C. D. Houtman
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| Open AccessIL-6/ERK signaling pathway participates in type I IFN-programmed, unconventional M2-like macrophage polarization
- Limin Yang
- , Panpan Guo
- & Jianghuai Liu
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| Open AccessThe LRP1/CD91 ligands, tissue-type plasminogen activator, α2-macroglobulin, and soluble cellular prion protein have distinct co-receptor requirements for activation of cell-signaling
- Elisabetta Mantuano
- , Pardis Azmoon
- & Steven L. Gonias
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| Open AccessIκBζ regulates the development of nonalcoholic fatty liver disease through the attenuation of hepatic steatosis in mice
- Hideki Ishikawa
- , Morisada Hayakawa
- & Tsukasa Ohmori
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| Open AccessA novel lipidic peptide with potential to promote balanced effector-regulatory T cell responses
- Michael Agrez
- , Justyna Rzepecka
- & Laura Gallagher
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| Open AccessThe impact of short-term confinement on human innate immunity
- S. A. Ponomarev
- , A. A. Sadova
- & V. A. Shmarov
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| Open AccessOpen label safety and efficacy pilot to study mitigation of equine recurrent uveitis through topical suppressor of cytokine signaling-1 mimetic peptide
- Caryn E. Plummer
- , Timothy Polk
- & Joseph Larkin III
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| Open AccessIonic mitigation of CD4+ T cell metabolic fitness, Th1 central nervous system autoimmunity and Th2 asthmatic airway inflammation by therapeutic zinc
- Anna Krone
- , Yan Fu
- & Sascha Kahlfuss
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| Open AccessTunable heat shock protein-mediated NK cell responses are orchestrated by STAT1 in Antigen Presenting Cells
- Abigail L. Sedlacek
- , Lauren B. Kinner-Bibeau
- & Robert J. Binder
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| Open AccessVerloren negatively regulates the expression of IMD pathway dependent antimicrobial peptides in Drosophila
- Pragya Prakash
- , Arghyashree Roychowdhury-Sinha
- & Akira Goto
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| Open AccessCholesterol-dependent plasma membrane order (Lo) is critical for antigen-specific clonal expansion of CD4+ T cells
- Soumini Sengupta
- , Ritesh Karsalia
- & Anil K. Bamezai
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| Open AccessSuppression of human T cell activation by derivatives of glycerol monolaurate
- Micaela G. Fosdick
- , Pratik Rajesh Chheda
- & Jon C. D. Houtman
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| Open AccessTNFR1-d2 carrying the p.(Thr79Met) pathogenic variant is a potential novel actor of TNFα/TNFR1 signalling regulation in the pathophysiology of TRAPS
- Cécile Rittore
- , Déborah Méchin
- & Sylvie Grandemange
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| Open AccessUltra-purification of Lipopolysaccharides reveals species-specific signalling bias of TLR4: importance in macrophage function
- Matthew Stephens
- , Shan Liao
- & Pierre-Yves von der Weid
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| Open AccessT cell signaling and Treg dysfunction correlate to disease kinetics in IL-2Rα-KO autoimmune mice
- Genevieve N. Mullins
- , Kristen M. Valentine
- & Katrina K. Hoyer
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| Open AccessHIV-1 Tat – TLR4/MD2 interaction drives the expression of IDO-1 in monocytes derived dendritic cells through NF-κB dependent pathway
- Elmostafa Bahraoui
- , Manutea Serrero
- & Rémi Planès
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| Open AccessSnellenius manilae bracovirus suppresses the host immune system by regulating extracellular adenosine levels in Spodoptera litura
- Yuan Chang
- , Cheng-Kang Tang
- & Yueh-Lung Wu
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| Open AccessDevelopment of hypoallergenic variants of the major horse allergen Equ c 1 for immunotherapy by rational structure based engineering
- Jaana Haka
- , Merja H. Niemi
- & Juha Rouvinen
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| Open AccessTumor necrosis factor induces rapid down-regulation of TXNIP in human T cells
- Trine B. Levring
- , Martin Kongsbak-Wismann
- & Carsten Geisler
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| Open AccessPreventative and Therapeutic Effects of Low-dose Ionizing Radiation on the Allergic Response of Rat Basophilic Leukemia Cells
- Hae Mi Joo
- , Eun Hee Hong
- & Ji Young Kim
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| Open AccessIRAK3 modulates downstream innate immune signalling through its guanylate cyclase activity
- L. A. Freihat
- , J. I. Wheeler
- & H. R. Irving
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| Open AccessRole of NF-kappaB2-p100 in regulatory T cell homeostasis and activation
- Atika Dhar
- , Meenakshi Chawla
- & Soumen Basak
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| Open AccessPutative link between Polo-like kinases (PLKs) and Toll-like receptor (TLR) signaling in transformed and primary human immune cells
- Souhayla El Maadidi
- , Alexander N. R. Weber
- & Nicholas J. Gay
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| Open AccessTRAF3 regulates the oncogenic proteins Pim2 and c-Myc to restrain survival in normal and malignant B cells
- Amy L. Whillock
- , Nurbek Mambetsariev
- & Gail A. Bishop
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| Open AccessSeptins organize endoplasmic reticulum-plasma membrane junctions for STIM1-ORAI1 calcium signalling
- Zachary B. Katz
- , Chen Zhang
- & Patrick G. Hogan
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| Open AccessImmune adaptor SKAP1 acts a scaffold for Polo-like kinase 1 (PLK1) for the optimal cell cycling of T-cells
- Monika Raab
- , Klaus Strebhardt
- & Christopher E. Rudd
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| Open AccessActivation of Toll-like Receptor 2 (TLR2) induces Interleukin-6 trans-signaling
- Charlotte M. Flynn
- , Yvonne Garbers
- & Christoph Garbers
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| Open AccessHSV-1\EGFP stimulates miR-146a expression in a NF-κB-dependent manner in monocytic THP-1 cells
- Assunta Venuti
- , Maria Musarra-Pizzo
- & Maria Teresa Sciortino
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| Open AccessElevated pre-activation basal level of nuclear NF-κB in native macrophages accelerates LPS-induced translocation of cytosolic NF-κB into the cell nucleus
- Alexander V. Bagaev
- , Anastasiya Y. Garaeva
- & Fazly I. Ataullakhanov
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| Open AccessUSP18 and ISG15 coordinately impact on SKP2 and cell cycle progression
- Françoise Vuillier
- , Zhi Li
- & Sandra Pellegrini
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| Open AccessInhibition of Tropomyosin Receptor Kinase A Signaling Negatively Regulates Megakaryopoiesis and induces Thrombopoiesis
- Ayse Kizilyer
- , Meera V. Singh
- & Sanjay B. Maggirwar
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| Open AccessEndogenous Neurosteroid (3α,5α)3-Hydroxypregnan-20-one Inhibits Toll-like-4 Receptor Activation and Pro-inflammatory Signaling in Macrophages and Brain
- Irina Balan
- , Matthew C. Beattie
- & A. Leslie Morrow
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| Open AccessCryopreservation of primary B cells minimally influences their signaling responses
- Johanne U. Hermansen
- , Geir E. Tjønnfjord
- & Sigrid S. Skånland
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| Open AccessROCK2, but not ROCK1 interacts with phosphorylated STAT3 and co-occupies TH17/TFH gene promoters in TH17-activated human T cells
- Wei Chen
- , Melanie S. Nyuydzefe
- & Alexandra Zanin-Zhorov
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| Open AccessAgeratina adenophora induces mice hepatotoxicity via ROS-NLRP3-mediated pyroptosis
- Wei Sun
- , Chaorong Zeng
- & Yanchun Hu
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| Open AccessInhibiting ex-vivo Th17 responses in Ankylosing Spondylitis by targeting Janus kinases
- Ariane Hammitzsch
- , Liye Chen
- & Paul Bowness
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| Open AccessMyD88 signaling causes autoimmune sialadenitis through formation of high endothelial venules and upregulation of LTβ receptor-mediated signaling
- Takeshi Into
- , Shumpei Niida
- & Ken-ichiro Shibata
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| Open AccessPolarity of CD4+ T cells towards the antigen presenting cell is regulated by the Lck adapter TSAd
- Greger Abrahamsen
- , Vibeke Sundvold-Gjerstad
- & Anne Spurkland
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| Open AccessInterplay between interferon regulatory factor 1 and BRD4 in the regulation of PD-L1 in pancreatic stellate cells
- Kazumi Ebine
- , Krishan Kumar
- & Hidayatullah G. Munshi
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| Open AccessTNFR2 ligation in human T regulatory cells enhances IL2-induced cell proliferation through the non-canonical NF-κB pathway
- Jun Wang
- , Ricardo Ferreira
- & John R. Bradley
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| Open AccessButyrate produced by gut commensal bacteria activates TGF-beta1 expression through the transcription factor SP1 in human intestinal epithelial cells
- Camille Martin-Gallausiaux
- , Fabienne Béguet-Crespel
- & Nicolas Lapaque
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| Open AccessEgr2-independent, Klf1-mediated induction of PD-L1 in CD4+ T cells
- Shuzo Teruya
- , Tomohisa Okamura
- & Keishi Fujio
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| Open AccessPhysiological function of phospholipase D2 in anti-tumor immunity: regulation of CD8+ T lymphocyte proliferation
- Van Ngo Thai Bich
- , Tsunaki Hongu
- & Yasunori Kanaho
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| Open AccessThe Cish SH2 domain is essential for PLC-γ1 regulation in TCR stimulated CD8+ T cells
- Geoffrey Guittard
- , Ana Dios-Esponera
- & Lawrence E. Samelson
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| Open AccessImpedance-based analysis of Natural Killer cell stimulation
- Frank Fasbender
- & Carsten Watzl
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| Open AccessPhosphoinositides regulate the TCR/CD3 complex membrane dynamics and activation
- Nassima Chouaki Benmansour
- , Kilian Ruminski
- & Hai-Tao He