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| Open AccessANTXR1 deficiency promotes fibroblast senescence: implications for GAPO syndrome as a progeroid disorder
- Matthias Przyklenk
- , Shreya Karmacharya
- & Alvise Schiavinato
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| Open AccessChronic replication stress invokes mitochondria dysfunction via impaired parkin activity
- Tsuyoshi Kawabata
- , Reiko Sekiya
- & Tao-Sheng Li
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| Open AccessDietary E. coli promotes age-dependent chemotaxis decline in C. elegans
- Nadia Suryawinata
- , Rikuou Yokosawa
- & Kentaro Noma
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| Open AccessStudy of the mechanism by gentiopicroside protects against skin fibroblast glycation damage via the RAGE pathway
- Chunyu Chen
- , Xiaoxing Liu
- & Fan Yi
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| Open AccessIsolation of circulating endothelial cells provides tool to determine endothelial cell senescence in blood samples
- Katrin Kalies
- , Kai Knöpp
- & Daniel Sedding
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| Open AccessA strategy of novel molecular hydrogen-producing antioxidative auxiliary system improves virus production in cell bioreactor
- Yu-Jing Zeng
- , Min-Kung Hsu
- & Hsian-Yu Wang
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| Open AccessCellular senescence is associated with osteonecrosis of the femoral head while mesenchymal stem cell conditioned medium inhibits bone collapse
- Masanori Okamoto
- , Hiroaki Nakashima
- & Shiro Imagama
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| Open AccessMitofusin 1 silencing decreases the senescent associated secretory phenotype, promotes immune cell recruitment and delays melanoma tumor growth after chemotherapy
- Doménica Tarallo
- , Jennyfer Martínez
- & Celia Quijano
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| Open AccessmiR-195b is required for proper cellular homeostasis in the elderly
- Maria del Mar Muñoz-Gallardo
- , Carlos Garcia-Padilla
- & Diego Franco
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| Open AccessNectin-4 regulates cellular senescence-associated enlargement of cell size
- Ryoko Katasho
- , Taiki Nagano
- & Shinji Kamada
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| Open AccessLINC01638 sustains human mesenchymal stem cell self-renewal and competency for osteogenic cell fate
- Jonathan A. R. Gordon
- , Coralee E. Tye
- & Jane B. Lian
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| Open AccessCRISPR imaging reveals chromatin fluctuation at the centromere region related to cellular senescence
- Hideaki Takata
- , Yumena Masuda
- & Nobuko Ohmido
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| Open AccessIL-1β is involved in docetaxel chemoresistance by regulating the formation of polyploid giant cancer cells in non-small cell lung cancer
- Song Zhao
- , Sining Xing
- & Huiying Yu
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| Open AccessAn immunomodulating peptide to counteract solar radiation-induced immunosuppression and DNA damage
- Michael Agrez
- , Mark Stephen Rybchyn
- & Laura Gallagher
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| Open AccessSIRT6-PAI-1 axis is a promising therapeutic target in aging-related bone metabolic disruption
- Alkebaier Aobulikasimu
- , Tao Liu
- & Yoshinori Asou
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| Open AccessDNA methylation variations and epigenetic aging in telomere biology disorders
- Olivia Carlund
- , Anna Norberg
- & Magnus Hultdin
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| Open AccessComparison of the effects of oxidative and inflammatory stresses on rat chondrocyte senescence
- Misaki Yagi
- , Kentaro Endo
- & Ichiro Sekiya
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| Open AccessThe oncogenic properties of the EWSR1::CREM fusion gene are associated with polyamine metabolism
- Heidi Kaprio
- , Arafat Siddiqui
- & Maria Gardberg
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| Open AccessStandard of care drugs do not modulate activity of senescent primary human lung fibroblasts
- Stephanie Badaro-Garcia
- , Miriam S. Hohmann
- & Cory M. Hogaboam
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| Open AccessImmortalized murine tenocyte cells: a novel and innovative tool for tendon research
- Gil Lola Oreff
- , Barbara Maurer
- & Florien Jenner
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| Open AccessACSL1 promotes imatinib-induced chronic myeloid leukemia cell senescence by regulating SIRT1/p53/p21 pathway
- Wen Liu
- , Xiaoying Zhu
- & Xiaojian Zhu
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| Open AccessDynamic biological characteristics of human bone marrow hematopoietic stem cell senescence
- Minhe Xiao
- , Peng Zhou
- & Yaping Wang
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| Open AccessThe effect of short-term refrigeration on platelet responsiveness
- Anna Kobsar
- , Karina Koehnlechner
- & Juergen Koessler
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| Open AccessPaternal age impairs in vitro embryo and in vivo fetal development in murine
- Larissa Araújo Stábile
- , Camilla Mota Mendes
- & Mayra Elena Ortiz D’ Ávila Assumpção
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| Open AccessSIRT1 upregulation promotes epithelial-mesenchymal transition by inducing senescence escape in endometriosis
- Minghua Wang
- , Yongqi Wu
- & Ping Li
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| Open AccessMonovalent ions and stress-induced senescence in human mesenchymal endometrial stem/stromal cells
- Alla Shatrova
- , Elena Burova
- & Irina Marakhova
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| Open AccessShort term treatment with a cocktail of rapamycin, acarbose and phenylbutyrate delays aging phenotypes in mice
- Zhou Jiang
- , Juan Wang
- & Warren Ladiges
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| Open AccessAltered TGFB1 regulated pathways promote accelerated tendon healing in the superhealer MRL/MpJ mouse
- Jacob G. Kallenbach
- , Margaret A. T. Freeberg
- & Hani A. Awad
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| Open AccessAutomated characterisation of microglia in ageing mice using image processing and supervised machine learning algorithms
- Soyoung Choi
- , Daniel Hill
- & Maria Francesca Cordeiro
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| Open AccessTrehangelins ameliorate inflammation-induced skin senescence by suppressing the epidermal YAP-CCN1 axis
- Mami Yokota
- , Yoshiyuki Kamiya
- & Tetsuhito Sakurai
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| Open AccessEstablishment and characterization of immortalized sweat gland myoepithelial cells
- Tomohisa Hayakawa
- , Fumitaka Fujita
- & Kiyotoshi Sekiguchi
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| Open AccessUnraveling the stepwise maturation of the yeast telomerase including a Cse1 and Mtr10 mediated quality control checkpoint
- Anna Greta Hirsch
- , Daniel Becker
- & Heike Krebber
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| Open AccessTGF-β1 is involved in senescence-related pathways in glomerular endothelial cells via p16 translocation and p21 induction
- Sayo Ueda
- , Tatsuya Tominaga
- & Kojiro Nagai
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| Open AccessTargeted clearance of senescent cells using an antibody-drug conjugate against a specific membrane marker
- Marta Poblocka
- , Akang Leonard Bassey
- & Salvador Macip
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| Open AccessThe prevalence of inorganic mercury in human cells increases during aging but decreases in the very old
- Roger Pamphlett
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| Open AccessTelomere associated gene expression as well as TERT protein level and telomerase activity are altered in the ovarian follicles of aged mice
- Esra Gozde Kosebent
- & Saffet Ozturk
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| Open AccessReversal of senescence-associated beta-galactosidase expression during in vitro three-dimensional tissue-engineering of human chondrocytes in a polymer scaffold
- Shojiro Katoh
- , Atsuki Fujimaru
- & Samuel J. K. Abraham
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| Open AccessProgerin impairs 3D genome organization and induces fragile telomeres by limiting the dNTP pools
- Anna Kychygina
- , Marina Dall’Osto
- & Laure Crabbe
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| Open AccessReproductive performance in houbara bustard is affected by the combined effects of age, inbreeding and number of generations in captivity
- Robin Rabier
- , Loïc Lesobre
- & Alexandre Robert
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| Open AccessTotal body irradiation causes a chronic decrease in antioxidant levels
- Lue Sun
- , Yohei Inaba
- & Takashi Moritake
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| Open AccessTelomere attrition rates are associated with weather conditions and predict productive lifespan in dairy cattle
- Luise A. Seeker
- , Sarah L. Underwood
- & Daniel H. Nussey
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| Open AccessLong-term exposure of human endothelial cells to metformin modulates miRNAs and isomiRs
- Angelica Giuliani
- , Eric Londin
- & Jacopo Sabbatinelli
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| Open AccessTERT promoter alterations could provide a solution for Peto’s paradox in rodents
- Balázs Vedelek
- , Asha Kiran Maddali
- & Imre M. Boros
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| Open AccessParity predicts biological age acceleration in post-menopausal, but not pre-menopausal, women
- Talia N. Shirazi
- , Waylon J. Hastings
- & Calen P. Ryan
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| Open AccessUrolithin A augments angiogenic pathways in skeletal muscle by bolstering NAD+ and SIRT1
- Nandini Ghosh
- , Amitava Das
- & Chandan K. Sen
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| Open AccessLongevity strategies in response to light in the reef coral Stylophora pistillata
- Alexandre Ottaviani
- , Rita Eid
- & Denis Allemand
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| Open AccessMagnetic separation of peripheral nerve-resident cells underscores key molecular features of human Schwann cells and fibroblasts: an immunochemical and transcriptomics approach
- Kaiwen Peng
- , David Sant
- & Paula V. Monje
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| Open AccessGenomic profiling of the transcription factor Zfp148 and its impact on the p53 pathway
- Zhiyuan V. Zou
- , Nadia Gul
- & Per Lindahl
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| Open AccessDepletion of senescent-like neuronal cells alleviates cisplatin-induced peripheral neuropathy in mice
- Scarlett Acklin
- , Manchao Zhang
- & Fen Xia