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| Open AccessNetwork analysis of the proteome and peptidome sheds light on human milk as a biological system
- Pieter M. Dekker
- , Sjef Boeren
- & Kasper A. Hettinga
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| Open AccessYeast 26S proteasome nuclear import is coupled to nucleus-specific degradation of the karyopherin adaptor protein Sts1
- Carolyn Allain Breckel
- , Zane M. Johnson
- & Mark Hochstrasser
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| Open AccessGlucose restriction in Saccharomyces cerevisiae modulates the phosphorylation pattern of the 20S proteasome and increases its activity
- Renata Naporano Bicev
- , Maximilia Frazão de Souza Degenhardt
- & Fernanda Marques da Cunha
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| Open AccessPrimate-specific isoform of Nedd4-1 regulates substrate binding via Ser/Thr phosphorylation and 14-3-3 binding
- George Kefalas
- & Daniela Rotin
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| Open AccessThe histone acetyl transferases CBP and p300 regulate stress response pathways in synovial fibroblasts at transcriptional and functional levels
- Monika Krošel
- , Marcel Gabathuler
- & Kerstin Klein
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| Open AccessStructure–function analysis of histone H2B and PCNA ubiquitination dynamics using deubiquitinase-deficient strains
- Kaitlin S. Radmall
- , Prakash K. Shukla
- & Mahesh B. Chandrasekharan
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| Open AccessImmobilized enzyme microreactors for analysis of tryptic peptides in β-casein and β-lactoglobulin
- Agnieszka Rodzik
- , Viorica Railean
- & Michał Szumski
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| Open AccessEvaluation of the NRF1-proteasome axis as a therapeutic target in breast cancer
- Holly A. Byers
- , Amy N. Brooks
- & Senthil K. Radhakrishnan
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| Open AccessInhibition of CysLTR1 reduces the levels of aggregated proteins in retinal pigment epithelial cells
- Andreas Koller
- , Susanne Maria Brunner
- & Andrea Trost
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| Open AccessCalcineurin-mediated dephosphorylation enhances the stability and transactivation of c-Myc
- Takahiro Masaki
- , Makoto Habara
- & Midori Shimada
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| Open AccessTau protein binds to the P53 E3 ubiquitin ligase MDM2
- Martina Sola
- , Azucena Rendon-Angel
- & Stéphanie Papin
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| Open AccessThe GET pathway is a major bottleneck for maintaining proteostasis in Saccharomyces cerevisiae
- Rebecca Josefson
- , Navinder Kumar
- & Thomas Nyström
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| Open AccessNEIL3-mediated proteasomal degradation facilitates the repair of cisplatin-induced DNA damage in human cells
- Umit Aliyaskarova
- , Yeldar Baiken
- & Regina Groisman
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| Open AccessUtilizing genetic code expansion to modify N-TIMP2 specificity towards MMP-2, MMP-9, and MMP-14
- Hezi Hayun
- , Matt Coban
- & Niv Papo
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| Open AccessAlpha 2-macroglobulin acts as a clearance factor in the lysosomal degradation of extracellular misfolded proteins
- Ayaka Tomihari
- , Mako Kiyota
- & Eisuke Itakura
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| Open AccessFMRP, FXR1 protein and Dlg4 mRNA, which are associated with fragile X syndrome, are involved in the ubiquitin–proteasome system
- Hideo Shimizu
- & Hirohiko Hohjoh
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| Open AccessAngiotensin II type 1a receptor deficiency alleviates muscle atrophy after denervation
- Suguru Takayama
- , Kazuho Inoue
- & Atsuko Kamijo-Ikemori
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| Open AccessDisruption of male fertility-critical Dcaf17 dysregulates mouse testis transcriptome
- Raed Abu-Dawud
- , Bhavesh V. Mistry
- & Abdullah M. Assiri
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| Open AccessHelical stability of the GnTV transmembrane domain impacts on SPPL3 dependent cleavage
- Alkmini A. Papadopoulou
- , Walter Stelzer
- & Regina Fluhrer
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| Open AccessInterphotoreceptor matrix proteoglycans IMPG1 and IMPG2 proteolyze in the SEA domain and reveal localization mutual dependency
- Benjamin Mitchell
- , Chloe Coulter
- & Ezequiel M. Salido
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| Open AccessUDP-glucose, cereblon-dependent proinsulin degrader
- Jaeyong Cho
- , Atsushi Miyagawa
- & Takeshi Imai
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| Open AccessAn integrated approach to the analysis of antioxidative peptides derived from Gouda cheese with a modified β-casein content
- Anna Iwaniak
- , Damir Mogut
- & Małgorzata Darewicz
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| Open AccessEfficient terminal erythroid differentiation requires the APC/C cofactor Cdh1 to limit replicative stress in erythroblasts
- Myriam Cuadrado
- , Javier Garzón
- & Irene García-Higuera
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| Open AccessSulforaphane suppresses the activity of sterol regulatory element-binding proteins (SREBPs) by promoting SREBP precursor degradation
- Shingo Miyata
- , Manami Kodaka
- & Jun Inoue
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| Open AccessProlonged treatment with the proteasome inhibitor MG-132 induces apoptosis in PC12 rat pheochromocytoma cells
- Oktávia Tarjányi
- , Julian Haerer
- & György Sétáló Jr.
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| Open AccessProteasomal turnover of the RhoGAP tumor suppressor DLC1 is regulated by HECTD1 and USP7
- Yannick Frey
- , Mirita Franz-Wachtel
- & Monilola A. Olayioye
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| Open AccessRobo4 is constitutively shed by ADAMs from endothelial cells and the shed Robo4 functions to inhibit Slit3-induced angiogenesis
- Wenyuan Xiao
- , Alejandro Pinilla-Baquero
- & Lianchun Wang
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| Open AccessA systematic approach for evaluating the role of surface-exposed loops in trypsin-like serine proteases applied to the 170 loop in coagulation factor VIIa
- Anders B. Sorensen
- , Per Jr. Greisen
- & Ole H. Olsen
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| Open AccessReduced ech-6 expression attenuates fat-induced lifespan shortening in C. elegans
- Yasmine J. Liu
- , Arwen W. Gao
- & Riekelt H. Houtkooper
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| Open AccessNovel regulation mechanism of adrenal cortisol and DHEA biosynthesis via the endogen ERAD inhibitor small VCP-interacting protein
- Recep Ilhan
- , Göklem Üner
- & Petek Ballar Kirmizibayrak
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| Open AccessEffects of intracellular calcium accumulation on proteins encoded by the major genes underlying amyotrophic lateral sclerosis
- Giovanni De Marco
- , Annarosa Lomartire
- & Andrea Calvo
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| Open AccessDisparate effects of MMP and TIMP modulation on coronary atherosclerosis and associated myocardial fibrosis
- Georgios Kremastiotis
- , Ishita Handa
- & Jason Johnson
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| Open AccessE3-ligase knock down revealed differential titin degradation by autophagy and the ubiquitin proteasome system
- Erik Müller
- , Senem Salcan
- & Sebastian Kötter
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| Open AccessZSWIM8 is a myogenic protein that partly prevents C2C12 differentiation
- Fumihiko Okumura
- , Nodoka Oki
- & Takumi Kamura
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| Open AccessExploration of collagen cavitation based on peptide electrolysis
- Rui Zhai
- , Hui Chen
- & Zhihua Shan
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| Open AccessDoxycycline promotes proteasome fitness in the central nervous system
- Edmund Charles Jenkins
- , Matthew J. O’Connell
- & Doris Germain
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| Open AccessReciprocal interaction between SIRT6 and APC/C regulates genomic stability
- Helin Wang
- , Kangze Feng
- & Haiteng Deng
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| Open AccessA conserved rhizobial peptidase that interacts with host-derived symbiotic peptides
- Alex B. Benedict
- , Prithwi Ghosh
- & Joel S. Griffitts
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| Open AccessADAM10 and ADAM17 regulate EGFR, c-Met and TNF RI signalling in liver regeneration and fibrosis
- Olga Zbodakova
- , Karel Chalupsky
- & Radislav Sedlacek
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| Open AccessA comparative study of synthetic winged peptides for absolute protein quantification
- Eliska Benesova
- , Veronika Vidova
- & Zdenek Spacil
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| Open AccessAngiotensin converting enzyme 2 is a novel target of the γ-secretase complex
- Alberto Bartolomé
- , Jiani Liang
- & Utpal B. Pajvani
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| Open AccessInhibition of ERK 1/2 kinases prevents tendon matrix breakdown
- Ulrich Blache
- , Stefania L. Wunderli
- & Jess G. Snedeker
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| Open AccessProtein cleavage influences surface protein presentation in Mycoplasma pneumoniae
- Iain J. Berry
- , Michael Widjaja
- & Steven P. Djordjevic
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| Open AccessA new ultradian rhythm in mammalian cell dry mass observed by holography
- Lamya Ghenim
- , Cédric Allier
- & Xavier Gidrol
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| Open AccessUSP24 stabilizes bromodomain containing proteins to promote lung cancer malignancy
- Shao-An Wang
- , Ming-Jer Young
- & Jan-Jong Hung
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| Open AccessFunctional impacts of the ubiquitin–proteasome system on DNA damage recognition in global genome nucleotide excision repair
- Wataru Sakai
- , Mayumi Yuasa-Sunagawa
- & Kaoru Sugasawa
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| Open AccessTargeting PSMD14 inhibits melanoma growth through SMAD3 stabilization
- Satoru Yokoyama
- , Yusuke Iwakami
- & Hiroaki Sakurai
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| Open AccessIdentification and characterization of the proteolytic flagellin from the common freshwater bacterium Hylemonella gracilis
- Ulrich Eckhard
- , Constantin Blöchl
- & Hans Brandstetter
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| Open AccessTagging the proteasome active site β5 causes tag specific phenotypes in yeast
- Kenrick A. Waite
- , Alicia Burris
- & Jeroen Roelofs