Pexophagy articles within Nature Communications

Featured

• Article
  09 January 2024 | Open Access

  Upregulated pexophagy limits the capacity of selective autophagy

  An accumulation of one substrate of selective autophagy can lead to autophagic degradation deficiencies. Here, the authors show that a pathogenic increase in a single autophagy pathway restricts another by consuming the cell’s autophagy capacity.

  • Kyla Germain
  • , Raphaella W. L. So
  •  & Peter K. Kim

• Article
  05 December 2022 | Open Access

  Pexophagy suppresses ROS-induced damage in leaf cells under high-intensity light

  Pexophagy plays a pivotal role in the selective removal of ROS-generating peroxisomes, which protects plants from oxidative damage during photosynthesis under high-intensity light.

  • Kazusato Oikawa
  • , Shino Goto-Yamada
  •  & Mikio Nishimura

• Article
  19 October 2020 | Open Access

  Hsc70/Stub1 promotes the removal of individual oxidatively stressed peroxisomes

  Pexophagy removes damaged peroxisomes, which are particularly prone to ROS formation. Here, the authors use light to induce peroxisome turnover by local ROS generation, showing STUB1 translocation is critical and might contribute to human disease.

  • Bo-Hua Chen
  • , Yao-Jen Chang
  •  & Wei Yuan Yang