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| Open AccessCharacterisation of a cyclic peptide that binds to the RAS binding domain of phosphoinositide 3-kinase p110α
- Mohamed Ismail
- , Stephen R. Martin
- & Julian Downward
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Article
| Open AccessAn mTOR feedback loop mediates the ‘flare’ (‘rebound’) response to MET tyrosine kinase inhibition
- D. M. Altintas
- , M. Cerqua
- & P. M. Comoglio
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| Open AccessConformation specific antagonistic high affinity antibodies to the RON receptor kinase for imaging and therapy
- Xin Yu Koh
- , Xiao Hui Koh
- & David Philip Lane
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| Open AccessMulti-omics investigation reveals functional specialization of transcriptional cyclin dependent kinases in cancer biology
- Micah G. Donovan
- , Matthew D. Galbraith
- & Joaquin M. Espinosa
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| Open AccessA six lipid metabolism related gene signature for predicting the prognosis of hepatocellular carcinoma
- Kequan Xu
- , Peng Xia
- & Xiao Zhang
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| Open AccessNew C3H KitN824K/WT cancer mouse model develops late-onset malignant mammary tumors with high penetrance
- Tanja Klein-Rodewald
- , Kateryna Micklich
- & Birgit Rathkolb
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| Open AccessIdentification and in silico analysis of noval alteration Arg420Gly in KIT proto oncogene among acute myeloid leukemia patients
- Afia Muhammad Akram
- , Mubashir Hassan
- & Muhammad Arshad Javed
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| Open AccessA pan-cancer analysis of the role of hexokinase II (HK2) in human tumors
- Ruiqi Li
- , Shuchong Mei
- & Fuming Zi
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| Open AccessBioinformatics analysis of prognostic value and immunological role of MeCP2 in pan-cancer
- Yanfeng Wang
- , Yunqing Zhang
- & Jing Zhang
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| Open AccessMED1, a novel binding partner of BRCA1, regulates homologous recombination and R-loop processing
- Harunori Honjoh
- , Michihiro Tanikawa
- & Yutaka Osuga
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| Open AccessGlobal microRNA expression profile in laryngeal carcinoma unveils new prognostic biomarkers and novel insights into field cancerization
- Todor M. Popov
- , Gergana Stancheva
- & Diana P. Popova
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| Open AccessTargeted-sequence of normal urothelium and tumor of patients with non-muscle invasive bladder cancer
- Yujiro Hayashi
- , Kazutoshi Fujita
- & Norio Nonomura
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| Open AccessTWIST1 induces proteasomal degradation of β-catenin during the differentiation of ovarian cancer stem-like cells
- Jiaqi Liu
- , Guang Shu
- & Gang Yin
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Article
| Open AccessEffects of mRNA expression of five Notch ligands on prognosis of gastric carcinoma
- Yunlong Li
- , Fengni Xie
- & Liu Hong
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Article
| Open AccessTGFβ-induced changes in membrane curvature influence Ras oncoprotein membrane localization
- Alexandros Damalas
- , Ivana Vonkova
- & Dimitrios Stamou
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Article
| Open AccessPAI-1 is a potential transcriptional silencer that supports bladder cancer cell activity
- Hideki Furuya
- , Yuka Sasaki
- & Charles J. Rosser
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Article
| Open AccessStructure and function of cancer-related developmentally regulated GTP-binding protein 1 (DRG1) is conserved between sponges and humans
- Silvestar Beljan
- , Kristina Dominko
- & Helena Ćetković
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| Open AccessOncogenic role and potential regulatory mechanism of topoisomerase IIα in a pan-cancer analysis
- Xiaobo Wang
- , Jinhua Wang
- & Bo Tang
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| Open AccessCRISPR activation screen identifies TGFβ-associated PEG10 as a crucial tumor suppressor in Ewing sarcoma
- Vadim Saratov
- , Quy A. Ngo
- & Beat W. Schäfer
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Article
| Open AccessUtility of plasma circulating tumor DNA and tumor DNA profiles in head and neck squamous cell carcinoma
- Nobuyuki Chikuie
- , Yuji Urabe
- & Sachio Takeno
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| Open AccessAXL/CDCP1/SRC axis confers acquired resistance to osimertinib in lung cancer
- Yuichi Murakami
- , Daiki Kusakabe
- & Mayumi Ono
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| Open AccessTargeting the translational machinery in gastrointestinal stromal tumors (GIST): a new therapeutic vulnerability
- Donna M. Lee
- , Angela Sun
- & Anette Duensing
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| Open AccessThe K-Ras(G12D)-inhibitory peptide KS-58 suppresses growth of murine CT26 colorectal cancer cell-derived tumors
- Kotaro Sakamoto
- , Bangzhong Lin
- & Shinsaku Nakagawa
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Article
| Open AccessIncreased migration and motility in XIAP-null cells mediated by the C-RAF protein kinase
- Lauren G. Russell
- , Lydia A. K. Davis
- & Niall S. Kenneth
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| Open AccessComprehensive analysis of epigenetics regulation, prognostic and the correlation with immune infiltrates of GPX7 in adult gliomas
- Wallax Augusto Silva Ferreira
- , Glauco Akelinghton Freire Vitiello
- & Edivaldo Herculano Correa de Oliveira
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| Open AccessOCT1-target neural gene PFN2 promotes tumor growth in androgen receptor-negative prostate cancer
- Daisuke Obinata
- , Daigo Funakoshi
- & Satoshi Inoue
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| Open AccessPatient demographics, clinicopathologic features, and outcomes in wild-type gastrointestinal stromal tumor: a national cohort analysis
- Tahsin M. Khan
- , Emily A. Verbus
- & Andrew M. Blakely
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| Open AccessYB1 associates with oncogenetic roles and poor prognosis in nasopharyngeal carcinoma
- Yuting Zhan
- , Xianyong Chen
- & Songqing Fan
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| Open AccessAn enhanced triple fluorescence flow-cytometry-based assay shows differential activation of the Notch signaling pathway by human papillomavirus E6 proteins
- JiaWen Lim
- , Elke Straub
- & Claudia Simon
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| Open AccessEnhanced O-GlcNAc modification induced by the RAS/MAPK/CDK1 pathway is required for SOX2 protein expression and generation of cancer stem cells
- Masahiro Shimizu
- , Hiroshi Shibuya
- & Nobuyuki Tanaka
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| Open AccessConcomitant KRAS mutations attenuate sensitivity of non-small cell lung cancer cells to KRAS G12C inhibition
- Tereza Vaclova
- , Atanu Chakraborty
- & Elza C. de Bruin
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| Open AccessCD97 is associated with mitogenic pathway activation, metabolic reprogramming, and immune microenvironment changes in glioblastoma
- Michael M. Safaee
- , Elaina J. Wang
- & Manish K. Aghi
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Article
| Open AccessRelevance of gene mutations and methylation to the growth of pancreatic intraductal papillary mucinous neoplasms based on pyrosequencing
- Go Asano
- , Katsuyuki Miyabe
- & Hiromi Kataoka
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| Open AccessObjective to identify and verify the regulatory mechanism of DTNBP1 as a prognostic marker for hepatocellular carcinoma
- Xianyi Cheng
- , Dezhi Li
- & Wei V. Zheng
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| Open AccessNovel ratio-metric features enable the identification of new driver genes across cancer types
- Malvika Sudhakar
- , Raghunathan Rengaswamy
- & Karthik Raman
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| Open AccessComparable genetic alteration profiles between gastric cancers with current and past Helicobacter pylori infection
- Sho Tsuyuki
- , Hideyuki Takeshima
- & Toshikazu Ushijima
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| Open AccessFirst-line osimertinib in elderly patients with epidermal growth factor receptor-mutated advanced non-small cell lung cancer: a retrospective multicenter study (HOT2002)
- Gaku Yamamoto
- , Hajime Asahina
- & Hirotoshi Akita
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| Open AccessCurcumin derivative ST09 modulates the miR-199a-5p/DDR1 axis and regulates proliferation and migration in ovarian cancer cells
- Febina Ravindran
- , Jinsha Koroth
- & Bibha Choudhary
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| Open AccessMachine learning random forest for predicting oncosomatic variant NGS analysis
- Eric Pellegrino
- , Coralie Jacques
- & L’Houcine Ouafik
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| Open AccessK15 promoter-driven enforced expression of NKIRAS exhibits tumor suppressive activity against the development of DMBA/TPA-induced skin tumors
- Kenji Tago
- , Satoshi Ohta
- & Ken Yanagisawa
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| Open AccessDLEU1 promotes oral squamous cell carcinoma progression by activating interferon-stimulated genes
- Yui Hatanaka
- , Takeshi Niinuma
- & Hiromu Suzuki
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| Open AccessAHA1 regulates cell migration and invasion via the EMT pathway in colorectal adenocarcinomas
- Dasom Kim
- , Ji Wook Moon
- & Ji-Yun Lee
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| Open AccessOncogenic signaling inhibits c-FLIPL expression and its non-apoptotic function during ECM-detachment
- Matyas Abel Tsegaye
- , Jianping He
- & Zachary T. Schafer
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| Open AccessRAS specific protease induces irreversible growth arrest via p27 in several KRAS mutant colorectal cancer cell lines
- Caleb K. Stubbs
- , Marco Biancucci
- & Karla J. F. Satchell
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| Open AccessAberrant activation of the Hedgehog signalling pathway in squamous cell carcinoma of the vulva as a potential target for cancer therapy
- Jason K. W. Yap
- , Khalil Uddin
- & Christopher W. Dawson
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| Open AccessSeroprevalence and molecular diversity of Human Herpesvirus 8 among people living with HIV in Brazzaville, Congo
- Gervillien Arnold Malonga
- , Aude Jary
- & Anne-Geneviève Marcelin
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| Open AccessRab1A promotes cell proliferation and migration by upregulating Gli1 in colorectal cancer
- Chaozhong Peng
- , Xiao Li
- & Wenqing Wu
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| Open AccessComparison of the outcome between immunotherapy alone or in combination with chemotherapy in EGFR-mutant non-small cell lung cancer
- Chia-I Shen
- , Heng-Sheng Chao
- & Yuh-Min Chen
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| Open AccessExpression patterns and prognostic value of RUNX genes in kidney cancer
- Ke Gao
- , Fang Zhang
- & Zhi-Ming Dai