Non-REM sleep articles within Nature

Featured

• Article | 07 December 2022

  A signalling pathway for transcriptional regulation of sleep amount in mice

  Virus-mediated somatic genetics experiments in adult mouse brain identify key roles of LKB1 and SIK3 upstream of HDAC4/5 and CREB in the transcriptional regulation of non-rapid eye movement sleep.

  • Rui Zhou
  • , Guodong Wang
  •  & Qinghua Liu

• Article | 11 August 2021

  A metabolic function of the hippocampal sharp wave-ripple

  Sharp wave-ripples from the hippocampus are shown to modulate peripheral glucose homeostasis in rats, offering insights into the mechanism that links sleep disruption and blood glucose regulation in type 2 diabetes.

  • David Tingley
  • , Kathryn McClain
  •  & György Buzsáki

• Letter | 23 August 2017

  Lhx6-positive GABA-releasing neurons of the zona incerta promote sleep

  GABAergic Lhx6⁺ neurons in the ventral zona incerta promote both rapid eye movement and non-rapid eye movement sleep and inhibit the activity of wake-promoting GABAergic and Hcrt⁺ neurons of the lateral hypothalamus.

  • Kai Liu
  • , Juhyun Kim
  •  & Seth Blackshaw

• Article | 02 November 2016

  Forward-genetics analysis of sleep in randomly mutagenized mice

  Two mutations affecting the sleep–wakefulness balance in mice are detected, showing that the SIK3 protein kinase is essential for determining daily wake time, and the NALCN cation channel regulates the duration of rapid eye movement sleep.

  • Hiromasa Funato
  • , Chika Miyoshi
  •  & Masashi Yanagisawa