Featured
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Article |
Flexible scaling and persistence of social vocal communication
A population of neurons is identified in the lateral preoptic area that can drive the full range of social communication sounds with affective scaling during mating in mice.
- Jingyi Chen
- , Jeffrey E. Markowitz
- & Lisa Stowers
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Letter |
A competitive inhibitory circuit for selection of active and passive fear responses
Competitive circuits in the amygdala of mice drive either freezing or flight behaviour in response to threat, and involve distinct neuronal subtypes.
- Jonathan P. Fadok
- , Sabine Krabbe
- & Andreas Lüthi
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Letter |
Serotonin engages an anxiety and fear-promoting circuit in the extended amygdala
A brain circuit is identified through which serotonin induces an anxiety-like state; this circuit also mediates the anxiety-like behaviour induced by acute administration of the selective serotonin reuptake inhibitor fluoxetine and may underlie the early adverse events that some patients with anxiety disorders have to these types of drugs.
- Catherine A. Marcinkiewcz
- , Christopher M. Mazzone
- & Thomas L. Kash
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Letter |
Rapid regulation of depression-related behaviours by control of midbrain dopamine neurons
Optogenetic induction of phasic, but not tonic, firing in VTA dopamine neurons induces susceptibility to stress in mice undergoing a subthreshold social-defeat paradigm and in previously resilient mice that have been subjected to repeated social-defeat stress, and this effect is projection-pathway specific.
- Dipesh Chaudhury
- , Jessica J. Walsh
- & Ming-Hu Han
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Research Highlights |
Ringing in the brain